XERS Xeris Biopharma Holdings, Inc.
company
SEC Filings & Insider Trading Activity 2026

CIK: 1867096
Health Care
Pharmaceutical Preparations 35 filings
Russell 2000

Latest Xeris Biopharma Holdings, Inc. (XERS) SEC EDGAR filings in 2026, including the most recent 10-K annual report filed on March 2, 2026, a 10-Q quarterly report filed on May 7, 2026, an 8-K current report filed on August 6, 2026. SignalX aggregates every new 10-K annual report, 10-Q quarterly report, 8-K current report, and Form 4 insider transaction for Xeris Biopharma Holdings, Inc. (XERS) (SEC CIK 1867096), with AI-powered section-by-section summaries updated daily.

10-Q: 14
8-K: 11
SC 13G: 5
10-K: 5

Latest 2026 SEC Filing Dates

10-K Annual Report
Mar 2, 2026
10-Q Quarterly Report
May 7, 2026
8-K Current Report
Aug 6, 2026

AI 10-K Annual Report Analysis
Latest 10-K (2025-12-31)

Business Overview

  • Commercial-stage biopharma focused on therapies for chronic endocrine and neurological diseases in the U.S., with three commercial products: Recorlev, Gvoke, Keveyis
  • Phase 3-ready XP-8121: once-weekly subcutaneous levothyroxine injection leveraging proprietary XeriSol tech, planned Phase 3 start in 2026
  • Strategic emphasis on pipeline leveraging proprietary non-aqueous formulation tech (XeriSol/XeriJect) for improved drug delivery and new licensing partnerships
  • Patent protection for key products: Recorlev (orphan drug exclusivity through 2028, patents to 2040), Gvoke patents to 2036; Keveyis lost orphan exclusivity in 2022, facing generic competition
  • Noteworthy: Positive Phase 2 data for XP-8121 with 72% patient preference for weekly injection; FDA agreed on single non-inferiority Phase 3 trial design

Risk Factors

  • Risk of SBA PPP Loan audit/enforcement under CARES Act until May 2026, potentially diverting management resources and incurring costs
  • Geopolitical and macroeconomic risks impairing capital access due to inflation, interest rates, bank failures, and financial market volatility
  • Supply chain and inventory risks with potential product returns exceeding reserves, reliant on third-party data accuracy for return estimates
  • Competitive threats to Recorlev from Corcept Therapeutics' Korlym, Recordati's Signifor LAR and Isturisa, and potential ketoconazole approval in US
  • Financial risk from $200M term loans and $33.6M 8.00% Convertible Notes secured by company assets, with restrictive covenants limiting operations

Management Discussion & Analysis

  • No revenue or profitability figures disclosed in the provided MD&A section
  • Financing cash inflow $11.4M in 2025 vs $36.2M in 2024; driven by $20.7M stock awards and $10.9M stock repurchases
  • Investing cash outflow $696K in 2025 vs inflow $4.9M in 2024 due to fewer short-term investment purchases
  • No segment performance data or forward-looking guidance included in the excerpt

Go deeper on Xeris Biopharma Holdings, Inc.

Ask AI about XERS filings. Chat with the 10-K, 10-Q, and 8-K for instant answers on financials, risks, and guidance.

Track institutional money. See which funds are building or cutting XERS positions, quarter over quarter.

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Annual Reports Archive
10-K

AI-powered analysis of Xeris Biopharma Holdings, Inc. (XERS) 10-K annual reports filed with SEC EDGAR.

Recent 8-K Filings
Current Reports

AI-powered analysis of Xeris Biopharma Holdings, Inc. (XERS) 8-K current reports disclosing material events.

Financial Summary
XBRL

FY2023FY2024FY2025
Profitability
Revenue-$203.1M$291.8M
Operating Income-$44.0M-$33.6M$24.9M
Net Income-$62.3M-$54.8M$554K
Op. Margin--16.6%8.5%
Net Margin--27.0%0.2%
Balance Sheet
Total Assets$322.6M$323.1M$383.5M
Equity-$6.8M-$29.6M$13.7M
ROE917.9%185.2%4.0%
Per Share
EPS$-0.45$-0.37$0.00
Cash Flow
Operating CF-$47.0M-$37.0M$28.6M

Source: XBRL financial data from Xeris Biopharma Holdings, Inc. (XERS) 10-K filings on SEC EDGAR. All figures in USD. Key metrics include revenue, net income, gross profit, gross profit margin, operating income, EPS (diluted), total assets, stockholders' equity, return on equity (ROE), operating cash flow, and capital expenditure.

Latest 2026 SEC Filings: 10-K, 10-Q, 8-K & Form 4

FormFiling DatePeriodAnalysisSEC
8-K
Aug 6, 2026---
8-K
Jul 17, 2026---
8-K
Jun 30, 2026---
8-K
Jun 11, 2026---
8-K
Jun 5, 2026--
8-K
May 7, 2026--
10-Q
May 7, 2026Mar 31, 2026-
8-K
Apr 21, 2026---
8-K
Mar 2, 2026-Analysis-
10-K
Mar 2, 2026Dec 31, 2025Analysis
8-K
Feb 27, 2026-Analysis-
8-K
Jan 8, 2026--
8-K
Dec 1, 2025--
10-Q
Nov 6, 2025Sep 30, 2025-
10-Q
Aug 7, 2025Jun 30, 2025-
10-Q
May 8, 2025Mar 31, 2025-
10-K
Mar 6, 2025Dec 31, 2024-
10-Q
Nov 8, 2024Sep 30, 2024-
10-Q
Aug 8, 2024Jun 30, 2024-
10-Q
May 9, 2024Mar 31, 2024-
10-K
Mar 6, 2024Dec 31, 2023-
SC 13G
Feb 13, 2024--
SC 13G
Jan 26, 2024--
10-Q
Nov 9, 2023Sep 30, 2023-
10-Q
Aug 8, 2023Jun 30, 2023-

13F Fund Holdings: Quarterly Trend

Latest: Q1 2026

Aggregate XERS share value held by 13F filers tracked by SignalX, by quarter.

Position changes: Q4 2025Q1 2026
Top Buyers
Top Sellers
Closed Positions

Source: 13F-HR filings on SEC EDGAR (aggregated from 166 fund-quarter rows). Reflects only 13F filers tracked by SignalX, not the full institutional ownership universe.

Frequently Asked Questions

What are the latest XERS SEC filings in 2026?

Xeris Biopharma Holdings, Inc. (XERS) has filed a 10-K annual report on March 2, 2026, a 10-Q quarterly report on May 7, 2026, an 8-K current report on August 6, 2026 with the SEC. SignalX tracks every new SEC EDGAR filing daily, including 10-K, 10-Q, 8-K, and Form 4 insider transactions, with AI-powered summaries of key sections.

When did XERS file its most recent 10-K annual report?

Xeris Biopharma Holdings, Inc. (XERS) filed its most recent 10-K annual report on March 2, 2026. The 10-K includes audited financial statements, business overview, risk factors, and management discussion, all available on SignalX with AI-generated summaries and XBRL financial data.

How do I view XERS 10-Q quarterly reports?

Xeris Biopharma Holdings, Inc. (XERS)'s most recent 10-Q quarterly report was filed on May 7, 2026. SignalX displays every XERS 10-Q with AI-generated summaries of the MD&A (Management Discussion & Analysis) and Risk Factors sections, plus links to the original SEC EDGAR document.

What 8-K current reports has XERS filed recently?

Xeris Biopharma Holdings, Inc. (XERS)'s most recent 8-K was filed on August 6, 2026. 8-K filings disclose material corporate events such as earnings releases, executive changes, mergers, and other significant developments. SignalX surfaces each 8-K with item-level summaries so you can quickly see what happened.

Where can I find XERS insider trading activity (Form 4)?

SignalX aggregates every XERS Form 4 insider transaction from SEC EDGAR. Form 4 reports show when officers, directors, and 10% shareholders buy or sell company stock, with transaction code, share count, and price per share.

How often does XERS file with the SEC?

Xeris Biopharma Holdings, Inc. (XERS) files a 10-K annual report once per year (typically within 60 days of fiscal year-end) and 10-Q quarterly reports three times per year. 8-K current reports are filed as needed when material events occur, and Form 4 insider transaction reports are due within two business days of a trade. SignalX monitors SEC EDGAR daily to surface every new XERS filing with AI-powered analysis.

What is the difference between 10-K, 10-Q, and 8-K SEC filings?

A 10-K is a comprehensive annual report with audited financials, business overview, and risk factors. A 10-Q is a shorter quarterly report with unaudited financials and management discussion. An 8-K is a current report filed when a material event occurs, such as earnings releases, executive changes, acquisitions, or other significant developments. SignalX provides AI-generated summaries for all three filing types for Xeris Biopharma Holdings, Inc. (XERS).

What is XERS's SEC CIK number?

Xeris Biopharma Holdings, Inc. (XERS)'s SEC CIK (Central Index Key) number is 1867096. The CIK is a unique identifier assigned by the SEC to every filing entity. You can use CIK 1867096 to look up all XERS filings on SEC EDGAR, or browse them here on SignalX with AI-powered analysis.

Where can I find XERS return on equity (ROE) and financial data?

SignalX extracts XBRL financial data from Xeris Biopharma Holdings, Inc. (XERS) 10-K annual filings, including revenue, net income, gross profit, operating income, EPS, total assets, stockholders' equity, and operating cash flow. Return on equity (ROE) can be derived from net income divided by stockholders' equity. Multi-year financial trends are displayed in the Financial Summary table above.

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