Xeris Biopharma Holdings, Inc. (XERS) FY2025 10-K Annual Report

Filed: Mar 2, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

Xeris Biopharma Holdings, Inc. (XERS) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Mar 2, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Xeris Biopharma Holdings, Inc. FY2025 10-K Analysis

Business Overview

  • Commercial-stage biopharma focused on therapies for chronic endocrine and neurological diseases in the U.S., with three commercial products: Recorlev, Gvoke, Keveyis
  • Phase 3-ready XP-8121: once-weekly subcutaneous levothyroxine injection leveraging proprietary XeriSol tech, planned Phase 3 start in 2026
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Management Discussion & Analysis

  • No revenue or profitability figures disclosed in the provided MD&A section
  • Financing cash inflow $11.4M in 2025 vs $36.2M in 2024; driven by $20.7M stock awards and $10.9M stock repurchases
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Risk Factors

  • Risk of SBA PPP Loan audit/enforcement under CARES Act until May 2026, potentially diverting management resources and incurring costs
  • Geopolitical and macroeconomic risks impairing capital access due to inflation, interest rates, bank failures, and financial market volatility
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Xeris Biopharma Holdings, Inc. FY2025 Key Financial Metrics
XBRL

Revenue

$292M

+43.7% YoY

Net Income

$554,000

+101.0% YoY

Operating Margin

8.5%

+2510bp YoY

Net Margin

0.2%

+2719bp YoY

ROE

4.0%

-18112bp YoY

Total Assets

$384M

+18.7% YoY

EPS (Diluted)

$0.00

+100.0% YoY

Operating Cash Flow

$29M

+177.4% YoY

Source: XBRL data from Xeris Biopharma Holdings, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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