SEPN Septerna, Inc.
company
SEC Filings & Insider Trading Activity 2026

CIK: 1984086
Health Care
Pharmaceutical Preparations 11 filings
Russell 2000

Latest Septerna, Inc. (SEPN) SEC EDGAR filings in 2026 — including the most recent 10-K annual report filed on March 9, 2026, a 10-Q quarterly report filed on November 10, 2025, an 8-K current report filed on April 13, 2026. SignalX aggregates every new 10-K annual report, 10-Q quarterly report, 8-K current report, and Form 4 insider transaction for Septerna, Inc. (SEPN) (SEC CIK 1984086), with AI-powered section-by-section summaries updated daily.

8-K: 5
10-Q: 4
10-K: 2

Latest 2026 SEC Filing Dates

10-K Annual Report
Mar 9, 2026
10-Q Quarterly Report
Nov 10, 2025
8-K Current Report
Apr 13, 2026

AI 8-K Current Report Analysis
Recent 8-K Filings

Filed Mar 9, 2026
8-K
Full analysis →

Item 2.02: Results of Operations and Financial Condition

  • Q4 and full-year 2025 financial results announced March 9, 2026
  • Full details in Exhibit 99.1 press release — primary source for revenue, cash, and pipeline metrics
Filed Mar 2, 2026
8-K
Full analysis →

Item 7.01: Regulation FD Disclosure

  • Septerna (SEPN) disclosed material information via Reg FD, with substantive content in Exhibits 99.1 and 99.2
  • "Furnished not filed" status limits legal liability under Exchange Act Section 18 — standard for investor presentations and operational updates

Item 8.01: Other Events

  • SEP-631 Phase 1 cleared with adverse event profile comparable to placebo — no severe/serious adverse events across all doses
  • Once-daily oral dosing supported by ~24-hour half-life and no food-effect restrictions — strong convenience profile for chronic disease use

Recent 8-K Filings
Current Reports

AI-powered analysis of Septerna, Inc. (SEPN) 8-K current reports disclosing material events.

Latest 2026 SEC Filings — 10-K, 10-Q, 8-K & Form 4

FormFiling DatePeriodAnalysisSEC
8-K
Apr 13, 2026
10-K
Mar 9, 2026Dec 31, 2025
8-K
Mar 9, 2026Analysis
8-K
Mar 2, 2026Analysis
8-K
Jan 12, 2026
8-K
Jan 8, 2026
10-Q
Nov 10, 2025Sep 30, 2025
10-Q
Aug 11, 2025Jun 30, 2025
10-Q
May 15, 2025Mar 31, 2025
10-K
Mar 27, 2025Dec 31, 2024
10-Q
Nov 20, 2024Sep 30, 2024

Frequently Asked Questions

What are the latest SEPN SEC filings in 2026?

Septerna, Inc. (SEPN) has filed a 10-K annual report on March 9, 2026, a 10-Q quarterly report on November 10, 2025, an 8-K current report on April 13, 2026 with the SEC. SignalX tracks every new SEC EDGAR filing daily, including 10-K, 10-Q, 8-K, and Form 4 insider transactions, with AI-powered summaries of key sections.

When did SEPN file its most recent 10-K annual report?

Septerna, Inc. (SEPN) filed its most recent 10-K annual report on March 9, 2026. The 10-K includes audited financial statements, business overview, risk factors, and management discussion, all available on SignalX with AI-generated summaries and XBRL financial data.

How do I view SEPN 10-Q quarterly reports?

Septerna, Inc. (SEPN)'s most recent 10-Q quarterly report was filed on November 10, 2025. SignalX displays every SEPN 10-Q with AI-generated summaries of the MD&A (Management Discussion & Analysis) and Risk Factors sections, plus links to the original SEC EDGAR document.

What 8-K current reports has SEPN filed recently?

Septerna, Inc. (SEPN)'s most recent 8-K was filed on April 13, 2026. 8-K filings disclose material corporate events such as earnings releases, executive changes, mergers, and other significant developments. SignalX surfaces each 8-K with item-level summaries so you can quickly see what happened.

Where can I find SEPN insider trading activity (Form 4)?

SignalX aggregates every SEPN Form 4 insider transaction from SEC EDGAR. Form 4 reports show when officers, directors, and 10% shareholders buy or sell company stock, with transaction code, share count, and price per share.

How often does SEPN file with the SEC?

Septerna, Inc. (SEPN) files a 10-K annual report once per year (typically within 60 days of fiscal year-end) and 10-Q quarterly reports three times per year. 8-K current reports are filed as needed when material events occur, and Form 4 insider transaction reports are due within two business days of a trade. SignalX monitors SEC EDGAR daily to surface every new SEPN filing with AI-powered analysis.

What is the difference between 10-K, 10-Q, and 8-K SEC filings?

A 10-K is a comprehensive annual report with audited financials, business overview, and risk factors. A 10-Q is a shorter quarterly report with unaudited financials and management discussion. An 8-K is a current report filed when a material event occurs — such as earnings releases, executive changes, acquisitions, or other significant developments. SignalX provides AI-generated summaries for all three filing types for Septerna, Inc. (SEPN).

What is SEPN's SEC CIK number?

Septerna, Inc. (SEPN)'s SEC CIK (Central Index Key) number is 1984086. The CIK is a unique identifier assigned by the SEC to every filing entity. You can use CIK 1984086 to look up all SEPN filings on SEC EDGAR, or browse them here on SignalX with AI-powered analysis.

Where can I find SEPN return on equity (ROE) and financial data?

SignalX extracts XBRL financial data from Septerna, Inc. (SEPN) 10-K annual filings, including revenue, net income, gross profit, operating income, EPS, total assets, stockholders' equity, and operating cash flow. Return on equity (ROE) can be derived from net income divided by stockholders' equity. Multi-year financial trends are displayed in the Financial Summary table above.

Stay on top of Septerna, Inc. SEC filings

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