IOVA IOVANCE BIOTHERAPEUTICS, INC.
company
SEC Filings & Insider Trading Activity 2026

CIK: 1425205
Health Care
Biological Products, (No Diagnostic Substances) 111 filings
Russell 2000

Latest IOVANCE BIOTHERAPEUTICS, INC. (IOVA) SEC EDGAR filings in 2026 — including the most recent 10-K annual report filed on February 24, 2026, a 10-Q quarterly report filed on May 7, 2026, an 8-K current report filed on June 10, 2026. SignalX aggregates every new 10-K annual report, 10-Q quarterly report, 8-K current report, and Form 4 insider transaction for IOVANCE BIOTHERAPEUTICS, INC. (IOVA) (SEC CIK 1425205), with AI-powered section-by-section summaries updated daily.

10-Q: 55
SC 13G: 29
10-K: 18
8-K: 5
SC 13D: 4

Latest 2026 SEC Filing Dates

10-K Annual Report
Feb 24, 2026
10-Q Quarterly Report
May 7, 2026
8-K Current Report
Jun 10, 2026

AI 10-K Annual Report Analysis
Latest 10-K (2025-12-31)

Business Overview

  • Core business: Commercial-stage biopharma pioneering individualized tumor infiltrating lymphocyte (TIL) cell therapies for solid tumor cancers
  • New/regulatory: Amtagvi approved in U.S. and Canada, pending UK/Australia 2026 approvals, withdrawn and resubmitting EU MAA in 2026
+3 more insights

Risk Factors

  • Cybersecurity risk from internal systems and CROs, requiring increased resources to counter sophisticated threats
  • Dependency on IT infrastructure vulnerable to security breaches impacting business operations
+3 more insights

Management Discussion & Analysis

  • Revenue $263.5M, up 61% YoY; Amtagvi $220.0M (up $116.5M), Proleukin $43.5M (down $17.0M)
  • Cost of sales $173.2M, up 86%; R&D $300.3M, up 9%; SG&A flat at $152.3M; total expenses $666.9M, up 19%
+3 more insights

Annual Reports Archive
10-K

AI-powered analysis of IOVANCE BIOTHERAPEUTICS, INC. (IOVA) 10-K annual reports filed with SEC EDGAR.

Quarterly Reports Archive
10-Q

AI-powered analysis of IOVANCE BIOTHERAPEUTICS, INC. (IOVA) 10-Q quarterly reports filed with SEC EDGAR.

Recent 8-K Filings
Current Reports

AI-powered analysis of IOVANCE BIOTHERAPEUTICS, INC. (IOVA) 8-K current reports disclosing material events.

Financial Summary
XBRL

FY2021FY2022FY2023FY2024FY2025
Profitability
Revenue$1.2M$164.1M$263.5M
Operating Income-$398.9M-$460.6M-$395.3M-$403.4M
Net Income-$342.3M-$395.9M-$444.0M-$372.2M-$391.0M
Op. Margin-38735.0%-240.9%-153.1%
Net Margin-37345.4%-226.8%-148.4%
Balance Sheet
Total Assets$664.0M$780.4M$910.4M$913.2M
Equity$499.6M$584.6M$710.4M$698.6M
ROE-79.2%-76.0%-52.4%-56.0%

Source: XBRL financial data from IOVANCE BIOTHERAPEUTICS, INC. (IOVA) 10-K filings on SEC EDGAR. All figures in USD. Key metrics include revenue, net income, gross profit, gross profit margin, operating income, EPS (diluted), total assets, stockholders' equity, return on equity (ROE), operating cash flow, and capital expenditure.

Latest 2026 SEC Filings — 10-K, 10-Q, 8-K & Form 4

FormFiling DatePeriodAnalysisSEC
8-K
Jun 10, 2026
8-K
May 7, 2026
10-Q
May 7, 2026Mar 31, 2026
8-K
Mar 20, 2026
8-K
Feb 24, 2026Analysis
10-K
Feb 24, 2026Dec 31, 2025Analysis
8-K
Jan 9, 2026
10-Q
Nov 6, 2025Sep 30, 2025Analysis
10-Q
Aug 7, 2025Jun 30, 2025
10-Q
May 8, 2025Mar 31, 2025
10-K
Feb 27, 2025Dec 31, 2024
10-Q
Nov 7, 2024Sep 30, 2024
10-Q
Aug 8, 2024Jun 30, 2024
10-Q
May 9, 2024Mar 31, 2024
SC 13G
Mar 1, 2024
10-K
Feb 28, 2024Dec 31, 2023
10-Q
Nov 7, 2023Sep 30, 2023
10-Q
Aug 8, 2023Jun 30, 2023
10-Q
May 10, 2023Mar 31, 2023
10-K
Feb 28, 2023Dec 31, 2022
SC 13G
Feb 17, 2023
SC 13G
Feb 3, 2023
SC 13G
Feb 2, 2023
SC 13G
Dec 30, 2022
10-Q
Nov 3, 2022Sep 30, 2022

Frequently Asked Questions

What are the latest IOVA SEC filings in 2026?

IOVANCE BIOTHERAPEUTICS, INC. (IOVA) has filed a 10-K annual report on February 24, 2026, a 10-Q quarterly report on May 7, 2026, an 8-K current report on June 10, 2026 with the SEC. SignalX tracks every new SEC EDGAR filing daily, including 10-K, 10-Q, 8-K, and Form 4 insider transactions, with AI-powered summaries of key sections.

When did IOVA file its most recent 10-K annual report?

IOVANCE BIOTHERAPEUTICS, INC. (IOVA) filed its most recent 10-K annual report on February 24, 2026. The 10-K includes audited financial statements, business overview, risk factors, and management discussion, all available on SignalX with AI-generated summaries and XBRL financial data.

How do I view IOVA 10-Q quarterly reports?

IOVANCE BIOTHERAPEUTICS, INC. (IOVA)'s most recent 10-Q quarterly report was filed on May 7, 2026. SignalX displays every IOVA 10-Q with AI-generated summaries of the MD&A (Management Discussion & Analysis) and Risk Factors sections, plus links to the original SEC EDGAR document.

What 8-K current reports has IOVA filed recently?

IOVANCE BIOTHERAPEUTICS, INC. (IOVA)'s most recent 8-K was filed on June 10, 2026. 8-K filings disclose material corporate events such as earnings releases, executive changes, mergers, and other significant developments. SignalX surfaces each 8-K with item-level summaries so you can quickly see what happened.

Where can I find IOVA insider trading activity (Form 4)?

SignalX aggregates every IOVA Form 4 insider transaction from SEC EDGAR. Form 4 reports show when officers, directors, and 10% shareholders buy or sell company stock, with transaction code, share count, and price per share.

How often does IOVA file with the SEC?

IOVANCE BIOTHERAPEUTICS, INC. (IOVA) files a 10-K annual report once per year (typically within 60 days of fiscal year-end) and 10-Q quarterly reports three times per year. 8-K current reports are filed as needed when material events occur, and Form 4 insider transaction reports are due within two business days of a trade. SignalX monitors SEC EDGAR daily to surface every new IOVA filing with AI-powered analysis.

What is the difference between 10-K, 10-Q, and 8-K SEC filings?

A 10-K is a comprehensive annual report with audited financials, business overview, and risk factors. A 10-Q is a shorter quarterly report with unaudited financials and management discussion. An 8-K is a current report filed when a material event occurs — such as earnings releases, executive changes, acquisitions, or other significant developments. SignalX provides AI-generated summaries for all three filing types for IOVANCE BIOTHERAPEUTICS, INC. (IOVA).

What is IOVA's SEC CIK number?

IOVANCE BIOTHERAPEUTICS, INC. (IOVA)'s SEC CIK (Central Index Key) number is 1425205. The CIK is a unique identifier assigned by the SEC to every filing entity. You can use CIK 1425205 to look up all IOVA filings on SEC EDGAR, or browse them here on SignalX with AI-powered analysis.

Where can I find IOVA return on equity (ROE) and financial data?

SignalX extracts XBRL financial data from IOVANCE BIOTHERAPEUTICS, INC. (IOVA) 10-K annual filings, including revenue, net income, gross profit, operating income, EPS, total assets, stockholders' equity, and operating cash flow. Return on equity (ROE) can be derived from net income divided by stockholders' equity. Multi-year financial trends are displayed in the Financial Summary table above.

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