IOVA IOVANCE BIOTHERAPEUTICS, INC.

company

SEC Filings & Insider Trading Activity 2026

Business Overview

• • Core business: Commercial-stage biopharma pioneering individualized tumor infiltrating lymphocyte (TIL) cell therapies for solid tumor cancers
• • New/regulatory: Amtagvi approved in U.S. and Canada, pending UK/Australia 2026 approvals, withdrawn and resubmitting EU MAA in 2026

Risk Factors

• • Cybersecurity risk from internal systems and CROs, requiring increased resources to counter sophisticated threats
• • Dependency on IT infrastructure vulnerable to security breaches impacting business operations

Management Discussion & Analysis

• • Revenue $263.5M, up 61% YoY; Amtagvi $220.0M (up $116.5M), Proleukin $43.5M (down $17.0M)
• • Cost of sales $173.2M, up 86%; R&D $300.3M, up 9%; SG&A flat at $152.3M; total expenses $666.9M, up 19%

Risk Factors

• • New risk: Strategic restructuring with 19% workforce reduction completed Sept 2025 to cut costs and extend cash runway
• • Updated financial risk: Raised $350M ATM equity facility with Jefferies in Aug 2025 to support operations and product commercialization

What are the latest IOVA SEC filings in 2026?

IOVANCE BIOTHERAPEUTICS, INC. (IOVA) has filed a 10-K annual report on February 24, 2026, a 10-Q quarterly report on November 6, 2025, an 8-K current report on March 20, 2026 with the SEC. SignalX tracks every new SEC EDGAR filing daily, including 10-K, 10-Q, 8-K, and Form 4 insider transactions, with AI-powered summaries of key sections.

When did IOVA file its most recent 10-K annual report?

IOVANCE BIOTHERAPEUTICS, INC. (IOVA) filed its most recent 10-K annual report on February 24, 2026. The 10-K includes audited financial statements, business overview, risk factors, and management discussion, all available on SignalX with AI-generated summaries and XBRL financial data.

How do I view IOVA 10-Q quarterly reports?

IOVANCE BIOTHERAPEUTICS, INC. (IOVA)'s most recent 10-Q quarterly report was filed on November 6, 2025. SignalX displays every IOVA 10-Q with AI-generated summaries of the MD&A (Management Discussion & Analysis) and Risk Factors sections, plus links to the original SEC EDGAR document.

What 8-K current reports has IOVA filed recently?

IOVANCE BIOTHERAPEUTICS, INC. (IOVA)'s most recent 8-K was filed on March 20, 2026. 8-K filings disclose material corporate events such as earnings releases, executive changes, mergers, and other significant developments. SignalX surfaces each 8-K with item-level summaries so you can quickly see what happened.

Where can I find IOVA insider trading activity (Form 4)?

SignalX aggregates every IOVA Form 4 insider transaction from SEC EDGAR. Form 4 reports show when officers, directors, and 10% shareholders buy or sell company stock, with transaction code, share count, and price per share.

How often does IOVA file with the SEC?

IOVANCE BIOTHERAPEUTICS, INC. (IOVA) files a 10-K annual report once per year (typically within 60 days of fiscal year-end) and 10-Q quarterly reports three times per year. 8-K current reports are filed as needed when material events occur, and Form 4 insider transaction reports are due within two business days of a trade. SignalX monitors SEC EDGAR daily to surface every new IOVA filing with AI-powered analysis.

What is the difference between 10-K, 10-Q, and 8-K SEC filings?

A 10-K is a comprehensive annual report with audited financials, business overview, and risk factors. A 10-Q is a shorter quarterly report with unaudited financials and management discussion. An 8-K is a current report filed when a material event occurs — such as earnings releases, executive changes, acquisitions, or other significant developments. SignalX provides AI-generated summaries for all three filing types for IOVANCE BIOTHERAPEUTICS, INC. (IOVA).

What is IOVA's SEC CIK number?

IOVANCE BIOTHERAPEUTICS, INC. (IOVA)'s SEC CIK (Central Index Key) number is 1425205. The CIK is a unique identifier assigned by the SEC to every filing entity. You can use CIK 1425205 to look up all IOVA filings on SEC EDGAR, or browse them here on SignalX with AI-powered analysis.

Where can I find IOVA return on equity (ROE) and financial data?

SignalX extracts XBRL financial data from IOVANCE BIOTHERAPEUTICS, INC. (IOVA) 10-K annual filings, including revenue, net income, gross profit, operating income, EPS, total assets, stockholders' equity, and operating cash flow. Return on equity (ROE) can be derived from net income divided by stockholders' equity. Multi-year financial trends are displayed in the Financial Summary table above.