8-K current report · filed Jul 20, 2026

4D Molecular Therapeutics, Inc. (FDMT) 8-K Current Report: July 20, 2026

Item 8.01FDMT overview

Short answer

4D Molecular Therapeutics, Inc. (FDMT) filed an 8-K current report with the SEC on July 20, 2026 reporting Item 8.01 (Other Events). Positive 2-year PRISM Phase 2b data support 4D-150 durability in broad wet AMD.

4D Molecular Therapeutics, Inc. 8-K event analysis

AI summary of each reported item and its exhibits

Item 8.01 · Other Events

  • Positive 2-year PRISM Phase 2b data support 4D-150 durability in broad wet AMD
  • Treatment burden reduced 78% overall, with 2.7 supplemental injections versus 12.0 projected for aflibercept
  • Recently diagnosed subgroup achieved 87% burden reduction, with 1.6 supplemental injections versus 12.0 projected
  • Phase 3 dose maintained efficacy response; 3E10 vg/eye selected for 4FRONT Phase 3 trials
  • Safety profile favorable: 2.8% mild inflammation and no new cases after 28 weeks; no reported hypotony or endophthalmitis

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