10-Q quarterly report · filed May 6, 2026

CASTLE BIOSCIENCES INC (CSTL) Q1 2026 10-Q Quarterly Report

Short answer

CASTLE BIOSCIENCES INC (CSTL) filed its Q1 2026 10-Q quarterly report on May 6, 2026 for the quarter ended Mar 31, 2026. Quarterly revenue was $84M (down 4.9% year over year) with net income of −$15M.

Q1 2026 key financials · XBRL

Revenue
$84M
−4.9% YoY
Net income
−$15M
+43.8% YoY
Operating margin
-22.0%
EPS (diluted)
−$0.49
+45.6% YoY

Source: XBRL data from the CASTLE BIOSCIENCES INC (CSTL) Q1 2026 10-Q on SEC EDGAR. USD.

CASTLE BIOSCIENCES INC Q1 2026 10-Q analysis

AI summary of MD&A and risk factor updates

Management Discussion & Analysis

  • Test reports 26,933, up 10% YoY; dermatology 14,696, up 6%, while TissueCypher 11,745, up 58%
  • AdvanceAD-Tx received approximately 650 orders during Q1 limited-access launch
  • DecisionDx-SCC worst-performing line, 3,702 reports vs 4,375 YoY
  • Management plans phased AdvanceAD-Tx availability throughout remainder of 2026
  • Headwinds include reimbursement uncertainty, macroeconomic disruptions, tariffs, higher interest rates, and Medicare noncoverage of DecisionDx-SCC

Risk Factors

  • New geopolitical risk: U.S.-Iran conflict since February 2026, with sanctions, export controls, and Strait of Hormuz closure risk
  • Most material update: DecisionDx-SCC noncovered under Novitas LCD effective April 24, 2025, reducing expected 2026 revenue contribution
  • Regulatory reimbursement risk: MolDX placed DecisionDx-SCC reconsideration on waiting list without scheduled Open Meeting date
  • Operational market risk: Revenue primarily dependent on DecisionDx-Melanoma and TissueCypher sales for the next several years
  • Financial risk: March 31, 2026 net loss $14.5 million and accumulated deficit $238.8 million

Generated from the filing text; verify against the original. 10-K vs 10-Q vs 8-K

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