Alnylam Pharmaceuticals (ALNY) Q3 2025 10-Q Quarterly Report

Filed: Oct 30, 2025Period ending Sep 30, 2025
Health Care
Pharmaceutical PreparationsSEC EDGAR

Alnylam Pharmaceuticals (ALNY) 10-Q quarterly report for Q3 2025, filed with SEC EDGAR on Oct 30, 2025 for the fiscal period ending Sep 30, 2025. This page provides AI-powered analysis including management discussion & analysis (MD&A), risk factor updates, and key quarterly financial data such as revenue and net income extracted from XBRL.

Alnylam Pharmaceuticals Q3 2025 10-Q Analysis

Management Discussion & Analysis

  • No quarterly revenue or YoY figures disclosed in this MD&A excerpt
  • No profitability or margin data provided for current quarter or YoY comparison
  • No segment or product line performance data included
  • Cash, equivalents, marketable securities, and Revolving Credit Agreement availability deemed sufficient for next 12 months as of Sept 30, 2025
  • Management warns potential need for significant additional funds earlier due to development and commercialization risks

Risk Factors

  • New risk: AMVUTTRA U.S. launch March 2025 for ATTR amyloidosis with cardiomyopathy increases commercialization risk
  • Updated financial risk: Accumulated deficit $7.16B as of Sept 30, 2025; product revenues $851.1M Q3, $1.99B YTD with ongoing operating losses
  • Regulatory risk: Ongoing regulatory oversight plus potential liability from unapproved product promotion or off-label marketing
  • Operational risk: Dependence on collaborators Roche, Regeneron, Novartis, Sanofi for development, commercialization, and sales execution
  • Financial risk: $2.72B cash and equivalents exposed to credit, liquidity, market risks; significant foreign currency exposure especially JPY, EUR, GBP impacting revenues and expenses

Alnylam Pharmaceuticals Q3 2025 Quarterly Financials
XBRL

Revenue

$1.2B

+149.3% YoY +61.4% QoQ

Net Income

$251M

+325.0% YoY +478.8% QoQ

Net Margin

20.1%

+4238bp YoY +2867bp QoQ

Source: XBRL data from Alnylam Pharmaceuticals Q3 2025 10-Q filing on SEC EDGAR. All figures in USD.

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