GeneDx Holdings Corp. (WGS) FY2025 10-K Annual Report

Filed: Feb 23, 2026
Health Care
Services-Health ServicesSEC EDGAR

GeneDx Holdings Corp. (WGS) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 23, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

GeneDx Holdings Corp. FY2025 10-K Analysis

Business Overview

  • Core business model: Provider of clinical exome and genome sequencing diagnostics powered by proprietary GeneDx Infinity™ rare disease dataset
  • New emphasis on rapid and ultraRapid genomes, medium/long-read sequencing, and multimodal genomic analysis expansion in 2025
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Management Discussion & Analysis

  • Revenue and profitability details not provided in the excerpt
  • No segment performance data disclosed
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Risk Factors

  • Regulatory risk: $42M settlement agreement with third-party payor for alleged overpayments to Legacy Sema4, $2M remaining payments as of Dec 31, 2025
  • Macroeconomic risk: reliance on reimbursement approvals from commercial and Medicaid payors, with 18% average reimbursement rate increase in 2025 impacting revenue
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GeneDx Holdings Corp. FY2025 Key Financial Metrics
XBRL

Revenue

$428M

+40.0% YoY

Net Income

-$21M

+59.8% YoY

Gross Margin

69.7%

+610bp YoY

Operating Margin

-3.1%

+454bp YoY

Net Margin

-4.9%

+1220bp YoY

ROE

-6.8%

+1450bp YoY

Total Assets

$524M

+24.9% YoY

EPS (Diluted)

$-0.73

+62.4% YoY

Operating Cash Flow

$33M

+216.8% YoY

Source: XBRL data from GeneDx Holdings Corp. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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