10-Q quarterly report · filed Nov 4, 2025

Spyre Therapeutics, Inc. (SYRE) Q3 2025 10-Q Quarterly Report

Short answer

Spyre Therapeutics, Inc. (SYRE) filed its Q3 2025 10-Q quarterly report on Nov 4, 2025 for the quarter ended Sep 30, 2025.

Q3 2025 key financials · XBRL

Net income
−$11M
+83.8% YoY · +69.5% QoQ
EPS (diluted)
−$0.15
+89.4% YoY · +86.2% QoQ

Source: XBRL data from the Spyre Therapeutics, Inc. (SYRE) Q3 2025 10-Q on SEC EDGAR. USD.

Spyre Therapeutics, Inc. Q3 2025 10-Q analysis

AI summary of MD&A and risk factor updates

Risk Factors

  • New material weakness in internal controls discovered Q4 2024 led to restatements of prior net loss per share disclosures
  • Going concern risk heightened by potential difficulty raising capital amid macroeconomic volatility and intensified biotech funding competition
  • FDA and other government agency disruptions, including potential shutdowns, may delay clinical trial review and product approvals
  • Intense competition from larger biopharma firms and emerging companies threatens clinical trial recruitment and future market penetration
  • Cash, cash equivalents, and marketable securities totaled $486.2 million as of September 30, 2025, with ongoing capital needs to fund operations

Generated from the filing text; verify against the original. 10-K vs 10-Q vs 8-K

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