10-Q quarterly report · filed Aug 4, 2026

RHYTHM PHARMACEUTICALS, INC. (RYTM) Q2 2026 10-Q Quarterly Report

Short answer

RHYTHM PHARMACEUTICALS, INC. (RYTM) filed its Q2 2026 10-Q quarterly report on Aug 4, 2026 for the quarter ended Jun 30, 2026. Quarterly revenue was $71M (up 46.9% year over year) with net income of −$49M.

Q2 2026 key financials · XBRL

Revenue
$71M
+46.9% YoY · +18.5% QoQ
Net income
−$49M
−5.7% YoY · +11.4% QoQ
Operating margin
-68.1%
EPS (diluted)
−$0.74
+1.3% YoY · +10.8% QoQ

Source: XBRL data from the RHYTHM PHARMACEUTICALS, INC. (RYTM) Q2 2026 10-Q on SEC EDGAR. USD.

RHYTHM PHARMACEUTICALS, INC. Q2 2026 10-Q analysis

AI summary of MD&A and risk factor updates

Management Discussion & Analysis

  • Product revenue $71.3M in Q2 2026, up 19% sequentially; no year-ago quarterly revenue disclosed
  • U.S. revenue $51.0M, up $14.1M or 38% sequentially; ex-U.S. revenue $20.3M, down $2.9M or 13%
  • Net loss $49.3M vs $46.6M YoY; operating-margin percentages not disclosed
  • Cash, cash equivalents and short-term investments $330.9M at June 30, 2026; expected funding for at least 24 months
  • Near-term milestones: Japan launch by year-end 2026, bivamelagon Phase 3 initiation by year-end 2026, Europe launches beginning 2027

Risk Factors

  • Newly triggered CHI-program risk: February 2023 Xinvento acquisition remains discovery-stage, with no expected revenue for many years
  • Most material financial update: continued losses, including $49.3 million quarterly net loss and $1,456.8 million accumulated deficit
  • Regulatory risk: later-stage setmelanotide trials may fail to replicate earlier results, jeopardizing additional indications and approvals
  • Near-term commercial risk: IMCIVREE commercialization remains early-stage across the United States, Canada, EU, and United Kingdom
  • Liquidity risk: $330.9 million cash and investments may require supplementation as development and commercialization expenses increase

Generated from the filing text; verify against the original. 10-K vs 10-Q vs 8-K

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