Protagonist Therapeutics, Inc (PTGX) Q3 2025 10-Q Quarterly Report

Filed: Nov 6, 2025Period ending Sep 30, 2025
Health Care
Pharmaceutical PreparationsSEC EDGAR

Protagonist Therapeutics, Inc (PTGX) 10-Q quarterly report for Q3 2025, filed with SEC EDGAR on Nov 6, 2025 for the fiscal period ending Sep 30, 2025. This page provides AI-powered analysis including management discussion & analysis (MD&A), risk factor updates, and key quarterly financial data such as revenue and net income extracted from XBRL.

Protagonist Therapeutics, Inc Q3 2025 10-Q Analysis

Risk Factors

  • New FDA disruption risk triggered by mass federal employee layoffs since January 2025 and ongoing government shutdown starting October 2025
  • Updated macroeconomic risk from U.S. tariffs up to 100% on imported branded pharmaceuticals announced September 2025 with unclear implementation timing
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Protagonist Therapeutics, Inc Q3 2025 Quarterly Financials
XBRL

Revenue

$5M

+0.8% YoY -15.0% QoQ

Net Income

-$39M

-18.5% YoY -13.1% QoQ

Operating Margin

-985.2%

-9847bp YoY -22712bp QoQ

Net Margin

-834.9%

-12449bp YoY -20791bp QoQ

ROE

-6.1%

Total Assets

$702M

EPS (Diluted)

$-0.62

-12.7% YoY -14.8% QoQ

Operating Cash Flow

-$2M

+93.0% YoY +93.3% QoQ

Source: XBRL data from Protagonist Therapeutics, Inc Q3 2025 10-Q filing on SEC EDGAR. All figures in USD.

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