10-Q quarterly report · filed Nov 4, 2025

Vaxcyte, Inc. (PCVX) Q3 2025 10-Q Quarterly Report

Short answer

Vaxcyte, Inc. (PCVX) filed its Q3 2025 10-Q quarterly report on Nov 4, 2025 for the quarter ended Sep 30, 2025.

Q3 2025 key financials · XBRL

Net income
−$213M
−106.4% YoY · −27.8% QoQ
EPS (diluted)
−$1.57
−89.2% YoY · −28.7% QoQ

Source: XBRL data from the Vaxcyte, Inc. (PCVX) Q3 2025 10-Q on SEC EDGAR. USD.

Vaxcyte, Inc. Q3 2025 10-Q analysis

AI summary of MD&A and risk factor updates

Risk Factors

  • New risk: Delays in drug substance manufacturing campaign due to Lonza capacity constraints impacting VAX-24 IND timelines
  • Updated financial risk: Net losses $212.8M Q3 2025 vs $103.1M Q3 2024; accumulated deficit $1.9B as of September 30, 2025
  • Regulatory risk: FDA may challenge VAX-31 Phase 3 Chemistry, Manufacturing and Controls strategy causing delays and added costs
  • Operational risk: Prioritization shift suspending VAX-A1, VAX-GI preclinical advancement and discontinuing VAX-PG due to efficacy concerns
  • Financial risk: Cash, cash equivalents and investments of $2.7B sufficient for 12+ months but need substantial future funding amid volatile markets

Generated from the filing text; verify against the original. 10-K vs 10-Q vs 8-K

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