Mirum Pharmaceuticals, Inc. (MIRM) FY2025 10-K Annual Report

Filed: Feb 25, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

Mirum Pharmaceuticals, Inc. (MIRM) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 25, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Mirum Pharmaceuticals, Inc. FY2025 10-K Analysis

Business Overview

  • Core biopharma focused on rare diseases with three approved medicines: Livmarli, Cholbam, Ctexli
  • Acquired asset portfolios in 2023-2026: Travere’s bile acid medicines and Bluejay’s brelovitug for hepatitis D treatment
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Risk Factors

  • Regulatory risk CREATES Act compliance, sample provision obligations for generics under December 2019 law
  • Geopolitical/macro exposure in EU and U.S. orphan drug exclusivity potentially shortened by EU legislative proposals
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Mirum Pharmaceuticals, Inc. FY2025 Key Financial Metrics
XBRL

Revenue

$521M

+54.7% YoY

Net Income

-$23M

+73.4% YoY

Operating Margin

-4.2%

+2176bp YoY

Net Margin

-4.5%

+2162bp YoY

ROE

-7.4%

+3155bp YoY

Total Assets

$843M

+25.7% YoY

EPS (Diluted)

$-0.47

+74.6% YoY

Operating Cash Flow

$56M

+440.7% YoY

Source: XBRL data from Mirum Pharmaceuticals, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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