10-K annual report · filed Mar 31, 2025

Maze Therapeutics, Inc. (MAZE) FY2024 10-K Annual Report

Short answer

Maze Therapeutics, Inc. (MAZE) filed its fiscal 2024 10-K annual report with the SEC on Mar 31, 2025. It reported revenue of $168M and net income of $52M.

  • Top risk flagged: No geopolitical or macroeconomic threat detailed in the section

FY2024 key financial metrics · XBRL

Revenue
$168M
Net income
$52M
Operating margin
34.4%
EPS (diluted)
$1.25
ROE
-16.8%
Operating cash flow
$76M

Source: XBRL data from the Maze Therapeutics, Inc. (MAZE) FY2024 10-K on SEC EDGAR. USD.

Maze Therapeutics, Inc. FY2024 10-K analysis

AI summary of each section, grounded in the filing text

Business Overview

  • Core business: Genetic medicine focused on novel drug discovery for complex diseases
  • No new products, services, or segments introduced or emphasized in FY 2025 filing
  • Continued emphasis on leadership with multiple new director appointments by March 31, 2025
  • Executive leadership consolidation: CEO Jason Coloma also acting as Principal Financial Officer
  • Filing lacks a formal business summary section, deviating from typical 10-K disclosures

Management Discussion & Analysis

  • Revenue $167.5M in 2024 vs $0 in 2023 from license agreements with Shionogi, Trace, Neurocrine
  • Net income $52.2M in 2024 vs net loss $100.4M in 2023; operating margin approx. 33.3% (income from operations $57.6M / revenue $167.5M) in 2024 vs negative in 2023
  • Best segment license revenue $167.5M in 2024 from Shionogi and others; worst segment research & development expenses $83.5M in 2024, up $9.6M YoY
  • Cash $196.8M end 2024; Series D preferred stock sale raised $70.8M; IPO proceeds net $127.8M in Feb 2025; no debt drawn from $50M credit facility
  • Management expects increasing R&D and G&A expenses; no commercial revenue forecasted; risk of financing shortfalls may delay operations or clinical programs

Risk Factors

  • No geopolitical or macroeconomic threat detailed in the section
  • Cybersecurity risk management led by Head of IT with 20+ years experience, ongoing monitoring and incident response program in place
  • No competitive or market disruption risk mentioned in the section
  • No financial or structural risk discussed in the section

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