Maze Therapeutics, Inc. (MAZE) FY2024 10-K Annual Report

Filed: Mar 31, 2025
Health Care
Biological Products, (No Diagnostic Substances)SEC EDGAR

Maze Therapeutics, Inc. (MAZE) 10-K annual report for fiscal year 2024, filed with SEC EDGAR on Mar 31, 2025. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Maze Therapeutics, Inc. FY2024 10-K Analysis

Business Overview

  • Core business: Genetic medicine focused on novel drug discovery for complex diseases
  • No new products, services, or segments introduced or emphasized in FY 2025 filing
  • Continued emphasis on leadership with multiple new director appointments by March 31, 2025
  • Executive leadership consolidation: CEO Jason Coloma also acting as Principal Financial Officer
  • Filing lacks a formal business summary section, deviating from typical 10-K disclosures

Management Discussion & Analysis

  • Revenue $167.5M in 2024 vs $0 in 2023 from license agreements with Shionogi, Trace, Neurocrine
  • Net income $52.2M in 2024 vs net loss $100.4M in 2023; operating margin approx. 33.3% (income from operations $57.6M / revenue $167.5M) in 2024 vs negative in 2023
  • Best segment license revenue $167.5M in 2024 from Shionogi and others; worst segment research & development expenses $83.5M in 2024, up $9.6M YoY
  • Cash $196.8M end 2024; Series D preferred stock sale raised $70.8M; IPO proceeds net $127.8M in Feb 2025; no debt drawn from $50M credit facility
  • Management expects increasing R&D and G&A expenses; no commercial revenue forecasted; risk of financing shortfalls may delay operations or clinical programs

Risk Factors

  • No specific regulatory or legal risk disclosed in the section
  • No geopolitical or macroeconomic threat detailed in the section
  • Cybersecurity risk management led by Head of IT with 20+ years experience, ongoing monitoring and incident response program in place
  • No competitive or market disruption risk mentioned in the section
  • No financial or structural risk discussed in the section

Maze Therapeutics, Inc. FY2024 Key Financial Metrics
XBRL

Revenue

$168M

Net Income

$52M

Operating Margin

34.4%

Net Margin

31.2%

ROE

-16.8%

Total Assets

$241M

EPS (Diluted)

$1.25

Operating Cash Flow

$76M

Source: XBRL data from Maze Therapeutics, Inc. FY2024 10-K filing on SEC EDGAR. All figures in USD.

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