Lantheus Holdings, Inc. (LNTH) FY2025 10-K Annual Report

Filed: Feb 26, 2026
Health Care
In Vitro & In Vivo Diagnostic SubstancesSEC EDGAR

Lantheus Holdings, Inc. (LNTH) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 26, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Lantheus Holdings, Inc. FY2025 10-K Analysis

Business Overview

  • Core business: Development, manufacturing, and commercialization of radiopharmaceutical and diagnostic imaging products
  • New launches: Acquisitions of Life Molecular (Neuraceq) and Evergreen, adding diagnostic imaging and CDMO services to portfolio in 2025
  • Strategic shifts: Discontinued AZEDRA in Q1 2024, sold TechneLite in 2026, focusing on higher-growth assets like Neuraceq and CDMO services
  • Notable metric: General & administrative expenses up $81.4M (42%) in 2025 due to acquisitions and litigation costs
  • Distinct fact: Paid $250M upfront for PNT2002 license but ceased development, deciding not to pursue NDA or further investment

Management Discussion & Analysis

  • Operating cash flow $390.1M in 2025 vs $544.8M in 2024, decrease driven by acquisitions and working capital timing
  • Investing cash outflow $627.1M in 2025 vs $204.5M in 2024, 2025 includes $268.9M for Evergreen and $306.7M for Life Molecular acquisitions
  • Financing cash used $316.5M in 2025 vs $115.7M in 2024, due to $300M stock repurchase in 2025 vs $100M in 2024
  • No specific revenue or margin figures disclosed in this section
  • Management highlights increased credit facility to $750M with extended maturity to 2029, expects cash plus credit availability to cover needs next 12+ months

Risk Factors

  • No specific or timely regulatory or legal risk detailed in the text
  • No concrete geopolitical or macroeconomic threat exposure disclosed
  • Operational risk from cybersecurity and data privacy requiring quarterly monitoring and oversight by Audit Committee
  • No named competitor or technology disrupting market environment mentioned
  • Key-person risk with CIO and CISO critical for risk management, each having ~30 years of industry experience

Lantheus Holdings, Inc. FY2025 Key Financial Metrics
XBRL

Revenue

$1.5B

+0.5% YoY

Net Income

$234M

-25.2% YoY

Gross Margin

61.1%

-333bp YoY

Operating Margin

20.2%

-963bp YoY

Net Margin

15.2%

-522bp YoY

ROE

21.4%

-729bp YoY

Total Assets

$2.2B

+12.5% YoY

EPS (Diluted)

$3.41

-21.8% YoY

Operating Cash Flow

$390M

-28.4% YoY

Source: XBRL data from Lantheus Holdings, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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