10-Q quarterly report · filed Oct 30, 2025

Insmed Incorporated (INSM) Q3 2025 10-Q Quarterly Report

Short answer

Insmed Incorporated (INSM) filed its Q3 2025 10-Q quarterly report on Oct 30, 2025 for the quarter ended Sep 30, 2025. Quarterly revenue was $142M (up 52.4% year over year) with net income of −$370M.

Q3 2025 key financials · XBRL

Revenue
$142M
+52.4% YoY · +32.5% QoQ
Net income
−$370M
−67.8% YoY · −15.0% QoQ
Operating margin
-257.1%
EPS (diluted)
−$1.77
−41.6% YoY · −4.1% QoQ

Source: XBRL data from the Insmed Incorporated (INSM) Q3 2025 10-Q on SEC EDGAR. USD.

Insmed Incorporated Q3 2025 10-Q analysis

AI summary of MD&A and risk factor updates

Risk Factors

  • New risk: Commercialization dependency on BRINSUPRI launched Q3 2025 in US with required regulatory approvals outside US
  • Most material update: Medicare reimbursement pressure from IRA potential impact on BRINSUPRI pricing and profitability
  • Impactful regulatory risk: Approval delays or denials in key markets including US, EU, Japan for ARIKAYCE front-line, BRINSUPRI, or brensocatib
  • Near-term operational risk: Building and maintaining effective sales and marketing capability for ARIKAYCE, BRINSUPRI in multiple regions
  • Financial risk: Revenue reversals from price refunds in France and 9.4% ARIKAYCE price cut in Japan in 2023 affecting financial results

Generated from the filing text; verify against the original. 10-K vs 10-Q vs 8-K

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