INSM Insmed Incorporated

FY2025 10-K
Filed: Feb 19, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

Insmed Incorporated (INSM) filed its fiscal year 2025 10-K annual report with the SEC on Feb 19, 2026. This page provides AI-powered analysis of the filing, including business overview, management discussion, risk factors, and key financial metrics from XBRL data.

AI Filing Analysis
FY2025 10-K

Business Overview

  • Core business model: Development and commercialization of specialty pharmaceuticals focusing on respiratory diseases, including key marketed products ARIKAYCE and BRINSUPRI
  • New product emphasis: BRINSUPRI launch in August 2025 generated $172.7M US sales in 2025, contributing to 66.7% overall revenue growth to $606.4M
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Management Discussion & Analysis

  • Revenue not disclosed in provided text, no YoY change available
  • Profitability or margin details not provided in the excerpt
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Risk Factors

  • FDA accelerated approval of ARIKAYCE contingent on successful ENCORE confirmatory trial with 425 patients enrolled as of Q4 2024
  • Exposure to inflation affecting suppliers, service providers, and partners across US, Europe, Japan, and global operations
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Financial Summary
XBRL

Revenue

$606M

Net Income

-$1.3B

Operating Margin

-205.6%

Net Margin

-210.5%

ROE

-172.8%

Total Assets

$2.3B

EPS (Diluted)

$-6.42

Operating Cash Flow

-$935M

Source: XBRL data from Insmed Incorporated FY2025 10-K filing on SEC EDGAR. All figures in USD.

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