IMNM Immunome Inc.

FY2025 10-K
Filed: Mar 3, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

Immunome Inc. (IMNM) filed its fiscal year 2025 10-K annual report with the SEC on Mar 3, 2026. This page provides AI-powered analysis of the filing, including business overview, management discussion, risk factors, and key financial metrics from XBRL data.

AI Filing Analysis
FY2025 10-K

Business Overview

  • Core business model: Development and commercialization of first- and best-in-class targeted oncology therapies with focus on antibody-drug conjugates (ADCs) and radioligand therapies (RLTs)
  • New emphasis on varegacestat for desmoid tumors with positive Phase 3 results and planned NDA submission Q2 2026
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Management Discussion & Analysis

  • Collaboration revenue $6.9M, down $2.1M YoY from $9.0M, ceasing after July 2025 termination
  • Operating margin improvement: operating loss $224.1M vs $305.8M, R&D expenses up to $177.3M vs $129.5M, G&A $43.8M vs $33.0M
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Risk Factors

  • Cybersecurity risk with potential regulatory fines, litigation, operational disruption, and reputational harm from IT system compromises
  • Key-person dependency on three senior IT officers managing cybersecurity, including Head of IT and Senior Director with 30+ years biotech experience
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Financial Summary
XBRL

Revenue

$7M

Net Income

-$212M

Operating Margin

-3228.8%

Net Margin

-3060.0%

ROE

-33.5%

Total Assets

$683M

EPS (Diluted)

$-2.43

Operating Cash Flow

-$191M

Source: XBRL data from Immunome Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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