10-Q quarterly report · filed Apr 27, 2026

Fulcrum Therapeutics, Inc. (FULC) Q1 2026 10-Q Quarterly Report

Short answer

Fulcrum Therapeutics, Inc. (FULC) filed its Q1 2026 10-Q quarterly report on Apr 27, 2026 for the quarter ended Mar 31, 2026.

Q1 2026 key financials · XBRL

Net income
−$19M
−7.0% YoY
EPS (diluted)
−$0.25
+10.7% YoY

Source: XBRL data from the Fulcrum Therapeutics, Inc. (FULC) Q1 2026 10-Q on SEC EDGAR. USD.

Fulcrum Therapeutics, Inc. Q1 2026 10-Q analysis

AI summary of MD&A and risk factor updates

Management Discussion & Analysis

  • Revenue $0, unchanged YoY; no product sales generated
  • Net loss $18.9M vs $17.7M YoY; operating loss $22.2M vs $20.4M
  • Pociredir external R&D $5.4M vs $4.3M; losmapimod $0 vs $1.0M
  • Cash, equivalents and securities $333.3M; operating cash use $18.8M vs $15.3M
  • Cash runway into 2029; registration-enabling trial planned for second half of 2026

Risk Factors

  • Newly highlighted tax risk from July 2025 OBBBA, which could materially affect future cash flow, financial condition, or results
  • Most material funding risk: $333.3 million liquidity projected through 2029, subject to potentially incorrect operating assumptions
  • Regulatory risk: additional FDA-required studies or clinical holds could delay pociredir development and increase expenses
  • Operational risk: pociredir is the only product candidate in active clinical development after losmapimod’s Phase 3 failure
  • Financial concentration: federal NOL carryforwards of $102.8 million limited to 80% of annual taxable income

Generated from the filing text; verify against the original. 10-K vs 10-Q vs 8-K

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