10-Q quarterly report · filed Aug 6, 2026

Denali Therapeutics Inc. (DNLI) Q2 2026 10-Q Quarterly Report

Short answer

Denali Therapeutics Inc. (DNLI) filed its Q2 2026 10-Q quarterly report on Aug 6, 2026 for the quarter ended Jun 30, 2026. Quarterly revenue was $4M with net income of −$128M.

Q2 2026 key financials · XBRL

Revenue
$4M
Net income
−$128M
−2.8% YoY · +0.7% QoQ
Operating margin
-3622.1%
EPS (diluted)
−$0.68
+5.6% YoY · +1.4% QoQ

Source: XBRL data from the Denali Therapeutics Inc. (DNLI) Q2 2026 10-Q on SEC EDGAR. USD.

Denali Therapeutics Inc. Q2 2026 10-Q analysis

AI summary of MD&A and risk factor updates

Management Discussion & Analysis

  • Revenue $3.6M, versus $0 prior-year quarter, driven by AVLAYAH commercial launch
  • Operating loss $130.5M, with operating margin -3,624.4% versus not meaningful prior-year margin
  • Net loss $127.6M versus $124.1M, with net margin -3,539.3% versus not meaningful
  • Best-performing product AVLAYAH, generating $3.6M revenue; no other commercial products
  • PRV sale generated $195.0M gross proceeds, received July 2026; Royalty Pharma funding added $200.0M gross proceeds in March
  • Continued operating losses expected as AVLAYAH commercialization and clinical programs advance; Takeda collaboration termination and failed LUMA endpoints emerging headwinds

Risk Factors

  • No risk-factors section provided; supplied text covers Items 2–6 rather than changed or carried-forward risks
  • Financing risk: $499.3 million private-placement proceeds subject to dilution from 26,046,065 pre-funded warrants
  • Compliance risk: private placement relies on Section 4(a)(2) and Rule 506(b) Regulation D exemptions
  • Governance risk: investor received director-nomination and additional registration rights
  • Market risk: director trading plan permits sales of up to 35,377 shares through September 2, 2027

Generated from the filing text; verify against the original. 10-K vs 10-Q vs 8-K

Other Denali Therapeutics Inc. quarterly reports

Ask about this quarter

Compare quarters, check guidance or see what insiders and funds did around the report.