CYTOKINETICS INC (CYTK) FY2025 10-K Annual Report

Filed: Feb 26, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

CYTOKINETICS INC (CYTK) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 26, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

CYTOKINETICS INC FY2025 10-K Analysis

Business Overview

  • Core business model: biopharmaceutical development and commercialization focused on muscle biology therapeutics for cardiovascular diseases
  • New product launch: MYQORZO approved by FDA in Dec 2025 for symptomatic oHCM, first commercial sales commenced Q1 2026
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Management Discussion & Analysis

  • Revenue $88.1M in 2025, up $69.6M from $18.5M in 2024, driven by license and milestone revenues from Bayer and Sanofi
  • Operating expenses rose sharply: R&D $416.0M (+23% YoY), G&A $284.3M (+32% YoY), reflecting clinical advancement and commercial readiness
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Risk Factors

  • Cybersecurity risk oversight led by Audit Committee with tech, risk, finance expertise and regular briefings from CISO, CEO, CFO
  • Dependence on Chief Information Security Officer Eric Brown with 10+ years cybersecurity experience for managing critical security operations
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CYTOKINETICS INC FY2025 Key Financial Metrics
XBRL

Revenue

$88M

+376.6% YoY

Net Income

-$785M

-33.2% YoY

Operating Margin

-695.4%

+220728bp YoY

Net Margin

-891.6%

+229951bp YoY

ROE

119.0%

-31649bp YoY

Total Assets

$1.4B

+1.6% YoY

EPS (Diluted)

$-6.54

-24.3% YoY

Operating Cash Flow

-$510M

-28.8% YoY

Source: XBRL data from CYTOKINETICS INC FY2025 10-K filing on SEC EDGAR. All figures in USD.

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