10-K annual report · filed Feb 6, 2026

Biogen (BIIB) FY2025 10-K Annual Report

Short answer

Biogen (BIIB) filed its fiscal 2025 10-K annual report with the SEC on Feb 6, 2026. It reported revenue of $9.9B (+2.2% year over year) and net income of $1.3B.

  • Top risk flagged: Regulatory risk: IRA Medicare Part D redesign caused $90 million 2025 revenue loss, impacting SKYCLARYS and MS portfolio with future pricing enforcement uncertainty

FY2025 key financial metrics · XBRL

Revenue
$9.9B
+2.2% YoY
Net income
$1.3B
−20.8% YoY
EPS (diluted)
$8.79
−21.4% YoY
ROE
7.1%
−2.7 pp YoY
Operating cash flow
$2.2B
−23.3% YoY

Source: XBRL data from the Biogen (BIIB) FY2025 10-K on SEC EDGAR. USD.

Biogen FY2025 10-K analysis

AI summary of each section, grounded in the filing text

Business Overview

  • Core business model: Global biopharmaceutical company developing and commercializing therapies primarily for neurology, specialized immunology, and rare diseases
  • New or emphasized segment: Expanded collaboration with Genentech on multiple anti-CD20 therapies including recently approved GAZYVA for lupus nephritis in Oct 2025
  • Strategic shift: Increased focus on biosimilars portfolio commercialization, including BENEPALI, IMRALDI, and FLIXABI as key growth drivers
  • Quantitative highlight: Acquired in-process research and development expense surged to $471.8M in 2025 from $61.5M in 2024, signaling aggressive pipeline investment
  • Noteworthy fact: Completed agreement to acquire Reata Pharmaceuticals (2023 filing) reflected in continued integration and intangible assets balancing $9.18B as of Dec 2025

Management Discussion & Analysis

  • No profitability or margin figures mentioned
  • Capital investments include new biologics manufacturing facility in Solothurn, Switzerland; expansion supports LEQEMBI and TYSABRI production
  • Future growth dependent on new product development, regulatory approvals, patent protection, and external business opportunities

Risk Factors

  • Regulatory risk: IRA Medicare Part D redesign caused $90 million 2025 revenue loss, impacting SKYCLARYS and MS portfolio with future pricing enforcement uncertainty
  • Geopolitical risk: Russia-Ukraine conflict may disrupt supply; revenues from Russia, Ukraine, Middle East each <2.0% of total revenue in 2023-2025
  • Supply chain risk: TECFIDERA, VUMERITY, LEQEMBI raw materials and components partly sourced outside U.S., with tariffs and supplier substitution risks
  • Competitive risk: TECFIDERA patent revoked by European Patent Office Nov 2025; multiple generic entrants causing significant revenue erosion
  • Financial risk: $1.75 billion 2025 Senior Notes issuance with proceeds used to redeem $4.050% notes; $4.2 billion cash and equivalents end 2025

Generated from the filing text; verify against the original. How to read a 10-K

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