Beam Therapeutics Inc. (BEAM) FY2025 10-K Annual Report

Filed: Feb 24, 2026
Health Care
Biological Products, (No Diagnostic Substances)SEC EDGAR

Beam Therapeutics Inc. (BEAM) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 24, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Beam Therapeutics Inc. FY2025 10-K Analysis

Business Overview

  • Core business: Fully integrated precision genetic medicines platform based on proprietary base editing gene editing technology without DNA double-strand breaks
  • New products/segments: Announced BEAM-304 for phenylketonuria (PKU) and advancing in vivo LNP liver-targeted base editors BEAM-302 (AATD) and BEAM-301 (GSDIa)
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Management Discussion & Analysis

  • Revenue $139.7M in 2025 vs $63.5M in 2024 and $377.7M in 2023, primarily from license and collaboration agreements
  • Net loss $80.0M in 2025 vs $376.7M loss in 2024 and $132.5M loss in 2023, accumulated deficit $1.6B at 2025 year-end
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Risk Factors

  • Cybersecurity risk oversight by Audit Committee with quarterly management updates and immediate alerts on significant incidents
  • Dependence on VP, IS with 25 years experience and CISSP and CISA certifications for cybersecurity program leadership
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Beam Therapeutics Inc. FY2025 Key Financial Metrics
XBRL

Revenue

$140M

+120.0% YoY

Net Income

-$80M

+78.8% YoY

Operating Margin

-274.6%

+37968bp YoY

Net Margin

-57.2%

+53588bp YoY

ROE

-6.5%

+4490bp YoY

Total Assets

$1.5B

+34.2% YoY

EPS (Diluted)

$-0.81

+82.3% YoY

Operating Cash Flow

-$345M

+0.6% YoY

Source: XBRL data from Beam Therapeutics Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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