BIOCRYST PHARMACEUTICALS INC (BCRX) FY2025 10-K Annual Report

Filed: Feb 26, 2026
Health Care
Biological Products, (No Diagnostic Substances)SEC EDGAR

BIOCRYST PHARMACEUTICALS INC (BCRX) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 26, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

BIOCRYST PHARMACEUTICALS INC FY2025 10-K Analysis

Business Overview

  • Core business model: Biopharmaceutical company focused on development and commercialization of pharmaceutical products, including rare disease treatments like ORLADEYO
  • Strategic shift: Sale of European ORLADEYO business with a Global Brand and Support Agreement limiting sole control over European brand positioning
+2 more insights

Management Discussion & Analysis

  • No revenue or YoY change figures provided in the MD&A section
  • No specific profitability or margin % data disclosed
+3 more insights

Risk Factors

  • FDA approval of ORLADEYO oral pellet for pediatric HAE patients aged 2 to <12 years in December 2025
  • Revenues from European ORLADEYO business divested in October 2025 for $254.5M cash proceeds
+3 more insights

BIOCRYST PHARMACEUTICALS INC FY2025 Key Financial Metrics
XBRL

Revenue

$875M

+94.1% YoY

Net Income

$264M

+396.9% YoY

Operating Margin

39.0%

+3954bp YoY

Net Margin

30.2%

+4988bp YoY

ROE

-221.4%

-24012bp YoY

Total Assets

$514M

+4.8% YoY

EPS (Diluted)

$1.21

+381.4% YoY

Operating Cash Flow

$347M

+767.8% YoY

Source: XBRL data from BIOCRYST PHARMACEUTICALS INC FY2025 10-K filing on SEC EDGAR. All figures in USD.

Get deeper insights on BIOCRYST PHARMACEUTICALS INC

Access full AI analysis, insider trading data, fund holdings, and cross-signal detection on SignalX.