10-Q quarterly report · filed Nov 3, 2025

Axsome Therapeutics, Inc. (AXSM) Q3 2025 10-Q Quarterly Report

Short answer

Axsome Therapeutics, Inc. (AXSM) filed its Q3 2025 10-Q quarterly report on Nov 3, 2025 for the quarter ended Sep 30, 2025. Quarterly revenue was $171M (up 63.2% year over year) with net income of −$47M.

Q3 2025 key financials · XBRL

Revenue
$171M
+63.2% YoY · +14.0% QoQ
Net income
−$47M
+26.9% YoY · +1.6% QoQ
Operating margin
-27.0%
EPS (diluted)
−$0.95
+29.1% YoY · +1.0% QoQ

Source: XBRL data from the Axsome Therapeutics, Inc. (AXSM) Q3 2025 10-Q on SEC EDGAR. USD.

Axsome Therapeutics, Inc. Q3 2025 10-Q analysis

AI summary of MD&A and risk factor updates

Risk Factors

  • New risk: Blackstone Loan Agreement with $570M facility triggered by May 8, 2025 closing, includes covenants restricting operations and $30M minimum liquidity covenant
  • Most materially updated risk: U.S. political uncertainty with 2025 federal government shutdown and 100% tariff on branded pharmaceuticals starting October 1, 2025, may disrupt operations
  • Regulatory/compliance risk: FDA reliance restrictions on safety/efficacy data could cause delays or extra costs in product development and commercialization
  • Operational/market risk: Geopolitical conflicts (Russia-Ukraine war, Israel-Hamas hostilities) causing market volatility and supply chain uncertainties impacting near-term performance
  • Financial risk: Outstanding loans bear variable SOFR +4.75% interest, maturity May 8, 2030, risk of accelerated repayment upon covenant breach affecting liquidity and business continuity

Generated from the filing text; verify against the original. 10-K vs 10-Q vs 8-K

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