AXSM Axsome Therapeutics, Inc.

FY2025 10-K
Filed: Feb 23, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

Axsome Therapeutics, Inc. (AXSM) filed its fiscal year 2025 10-K annual report with the SEC on Feb 23, 2026. This page provides AI-powered analysis of the filing, including business overview, management discussion, risk factors, and key financial metrics from XBRL data.

AI Filing Analysis
FY2025 10-K

Business Overview

  • Core business: Development, commercialization, and sales of pharmaceutical products for CNS disorders, including AUVELITY, SUNOSI, and launch of SYMBRAVO in 2025
  • New product: Commercial launch of SYMBRAVO began June 2025, generating $6.6 million in net sales for the year, no sales in prior year
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Risk Factors

  • Regulatory risk: FDA Breakthrough Therapy designation for AXS-05 for AD agitation may not expedite approval or guarantee marketing authorization
  • Geopolitical risk: EU sanctions on Russia extended to July 31, 2026, with potential supply chain and capital market disruptions impacting operations
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Financial Summary
XBRL

Revenue

$638M

Net Income

-$183M

Operating Margin

-26.1%

Net Margin

-28.7%

ROE

-207.5%

Total Assets

$690M

EPS (Diluted)

$-3.68

Operating Cash Flow

-$93M

Source: XBRL data from Axsome Therapeutics, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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