Apogee Therapeutics, Inc. (APGE) FY2025 10-K Annual Report

Filed: Mar 2, 2026
Health Care
Biological Products, (No Diagnostic Substances)SEC EDGAR

Apogee Therapeutics, Inc. (APGE) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Mar 2, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Apogee Therapeutics, Inc. FY2025 10-K Analysis

Business Overview

  • Core business: Clinical-stage biotech developing breakthrough therapeutics focused on protein modulation and drug candidates
  • Emphasis on zumilokibart (APG777) with $76.4M R&D spend in 2025, up $27.2M YoY, reflecting clinical trial expansion and manufacturing scale-up
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Management Discussion & Analysis

  • No revenue or profitability figures disclosed for fiscal year 2026 due to clinical-stage status
  • Pipeline focus on four antibody programs targeting inflammatory and immunology diseases, no segment financials given
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Apogee Therapeutics, Inc. FY2025 Key Financial Metrics
XBRL

Net Income

-$256M

-40.5% YoY

Total Assets

$937M

+24.3% YoY

EPS (Diluted)

$-4.22

-27.9% YoY

Operating Cash Flow

-$227M

-32.9% YoY

Source: XBRL data from Apogee Therapeutics, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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