ANAPTYSBIO, INC (ANAB) FY2025 10-K Annual Report

Filed: Mar 3, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

ANAPTYSBIO, INC (ANAB) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Mar 3, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

ANAPTYSBIO, INC FY2025 10-K Analysis

Business Overview

  • Business model: Biopharma company focusing on clinical development and commercialization collaborations, recognizing revenue mainly from milestones and royalties, not product sales
  • New monetization deals in 2024: Sold additional Jemperli royalty receivables for $50M, expanding prior $250M monetization agreement with Sagard
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Risk Factors

  • FDA acceptance of Vanda's imsidolimab BLA for GPP with target action date December 12, 2026, creating regulatory milestone risk
  • Exposure to global macroeconomic shifts impacting 424-patient rosnilimab Phase 2b RA trial conducted worldwide
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ANAPTYSBIO, INC FY2025 Key Financial Metrics
XBRL

Revenue

$235M

+157.0% YoY

Net Income

-$13M

+90.9% YoY

Operating Margin

20.4%

+14635bp YoY

Net Margin

-5.6%

+15346bp YoY

ROE

-35.6%

+16937bp YoY

Total Assets

$364M

-24.7% YoY

EPS (Diluted)

$-0.46

+91.0% YoY

Operating Cash Flow

$20M

+114.6% YoY

Source: XBRL data from ANAPTYSBIO, INC FY2025 10-K filing on SEC EDGAR. All figures in USD.

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