Amgen (AMGN) FY2025 10-K Annual Report

Filed: Feb 13, 2026
Health Care
Biological Products, (No Diagnostic Substances)SEC EDGAR

Amgen (AMGN) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 13, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Amgen FY2025 10-K Analysis

Business Overview

  • Core business: Biopharmaceutical company focused on innovative therapies for serious illnesses
  • NEW segment emphasis: Integration and conversion of Horizon Therapeutics' equity plans post-acquisition in October 2023
  • Strategic shift: Acquisition of Horizon Therapeutics with stock plans merged, ending Horizon plans for future grants as of Oct 6, 2023
  • Quantitative metric: 11,230,989 total securities issuable under Amgen and acquired equity plans, weighted-average exercise price $234.45
  • Noteworthy fact: Performance units granted in 2023-2025 can yield up to 200% of target shares based on performance goals

Management Discussion & Analysis

  • Cash and equivalents $9.1B in 2025 vs $12.0B in 2024, decline of $2.9B
  • Long-term debt decreased to $50.0B in 2025 from $56.5B in 2024
  • Dividends per share increased 6% YoY to $2.38 in 2025 from $2.25 in 2024
  • No stock repurchases in 2025, $200M repurchased in 2024, $6.8B repurchase authorization remains
  • Management confident in liquidity from operations, debt markets, and existing cash for capital needs and shareholder returns

Risk Factors

  • Litigation risk: Ongoing U.S. Antitrust trial with Regeneron; jury awarded $135.6M compensatory damages, potential trebling to $406.8M total damages
  • Geopolitical exposure: Patent disputes in Germany and Japan with Sanofi and Regeneron, including upheld EP’004 patent validity and ongoing appeals
  • Supply chain/operational vulnerability: Multi-jurisdictional patent litigation delays marketing; UPC actions and EPO oppositions prolong product launches like Repatha and PAVBLU
  • Competitive risk: Multiple biosimilar patent infringement lawsuits filed against five companies including Amneal, Hikma, Dr. Reddy’s, Alkem seeking to enter U.S. market for Prolia/XGEVA
  • Financial risk: $1.8B final U.S. repatriation tax payment made in 2025 under 2017 Tax Act, material cash outflow impacting liquidity planning

Amgen FY2025 Key Financial Metrics
XBRL

Revenue

$36.8B

+10.0% YoY

Net Income

$7.7B

+88.5% YoY

Operating Margin

24.7%

+299bp YoY

Net Margin

21.0%

+875bp YoY

ROE

89.1%

+1947bp YoY

Total Assets

$90.6B

-1.4% YoY

EPS (Diluted)

$14.23

+88.2% YoY

Operating Cash Flow

$10.0B

-13.3% YoY

Source: XBRL data from Amgen FY2025 10-K filing on SEC EDGAR. All figures in USD.

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