Amgen (AMGN) FY2025 10-K Annual Report

Filed: Feb 13, 2026
Health Care
Biological Products, (No Diagnostic Substances)SEC EDGAR

Amgen (AMGN) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 13, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Amgen FY2025 10-K Analysis

Business Overview

  • Core business: Biopharmaceutical company focused on innovative therapies for serious illnesses
  • NEW segment emphasis: Integration and conversion of Horizon Therapeutics' equity plans post-acquisition in October 2023
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Management Discussion & Analysis

  • Cash and equivalents $9.1B in 2025 vs $12.0B in 2024, decline of $2.9B
  • Long-term debt decreased to $50.0B in 2025 from $56.5B in 2024
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Risk Factors

  • Litigation risk: Ongoing U.S. Antitrust trial with Regeneron; jury awarded $135.6M compensatory damages, potential trebling to $406.8M total damages
  • Geopolitical exposure: Patent disputes in Germany and Japan with Sanofi and Regeneron, including upheld EP’004 patent validity and ongoing appeals
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Amgen FY2025 Key Financial Metrics
XBRL

Revenue

$36.8B

+10.0% YoY

Net Income

$7.7B

+88.5% YoY

Operating Margin

24.7%

+299bp YoY

Net Margin

21.0%

+875bp YoY

ROE

89.1%

+1947bp YoY

Total Assets

$90.6B

-1.4% YoY

EPS (Diluted)

$14.23

+88.2% YoY

Operating Cash Flow

$10.0B

-13.3% YoY

Source: XBRL data from Amgen FY2025 10-K filing on SEC EDGAR. All figures in USD.

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