ALUMIS INC. (ALMS) FY2024 10-K Annual Report

Filed: Mar 19, 2025
Health Care
Pharmaceutical PreparationsSEC EDGAR

ALUMIS INC. (ALMS) 10-K annual report for fiscal year 2024, filed with SEC EDGAR on Mar 19, 2025. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

ALUMIS INC. FY2024 10-K Analysis

Business Overview

  • Core business: Clinical-stage biopharmaceutical developing precision TYK2 inhibition therapies for immune-mediated diseases
  • New emphasis: Initiated Phase 1 trial of CNS-penetrant TYK2 inhibitor A-005 targeting MS and neurodegenerative diseases, reporting initial results in Dec 2024
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Management Discussion & Analysis

  • Revenue, profit, segment, cash flow, and guidance data not disclosed in provided text

Risk Factors

  • Regulatory risk: FDA current cGMP compliance reliance on CMOs for manufacturing, with no own facilities impacting supply chain control
  • Macroeconomic threat: ongoing Ukraine and Israel conflicts potentially disrupting operations and financing access amid global instability
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ALUMIS INC. FY2024 Key Financial Metrics
XBRL

Net Income

-$294M

-89.8% YoY

ROE

-113.1%

-15881bp YoY

Total Assets

$341M

+280.5% YoY

EPS (Diluted)

$-10.38

+85.6% YoY

Operating Cash Flow

-$255M

-96.3% YoY

Source: XBRL data from ALUMIS INC. FY2024 10-K filing on SEC EDGAR. All figures in USD.

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