10-Q quarterly report · filed Aug 6, 2026

Alector, Inc. (ALEC) Q2 2026 10-Q Quarterly Report

Short answer

Alector, Inc. (ALEC) filed its Q2 2026 10-Q quarterly report on Aug 6, 2026 for the quarter ended Jun 30, 2026. Quarterly revenue was $3M (down 57.8% year over year) with net income of −$23M.

Q2 2026 key financials · XBRL

Revenue
$3M
−57.8% YoY · +217.4% QoQ
Net income
−$23M
+24.7% YoY · −0.3% QoQ
Operating margin
-734.7%
EPS (diluted)
−$0.20
+33.3% YoY · +4.8% QoQ

Source: XBRL data from the Alector, Inc. (ALEC) Q2 2026 10-Q on SEC EDGAR. USD.

Alector, Inc. Q2 2026 10-Q analysis

AI summary of MD&A and risk factor updates

Management Discussion & Analysis

  • Collaboration revenue $3.3M, down $4.6M from $7.9M YoY, primarily lower AL101 AD revenue
  • Net loss $23.0M vs $30.5M YoY; operating loss $24.4M vs $34.1M
  • AL037/AL137 highest R&D spending at $5.0M; nivisnebart lowest at $0.7M
  • Cash, equivalents and securities $172.8M; operating cash used $84.0M versus $109.8M YoY
  • Runway at least through 2027; GSK termination effective January 2, 2027, with additional funding needed

Risk Factors

  • Newly triggered development setback: GSK discontinued nivisnebart’s Phase 2 PROGRESS-AD trial in April 2026 after interim futility analysis
  • Most material pipeline change: no active clinical trials after latozinemab, nivisnebart, and AL002 discontinuations
  • Regulatory risk: FDA or other agency staffing and funding changes could delay product development or commercialization
  • Near-term operational risk: preclinical-only pipeline leaves success dependent on advancing unproven neurodegenerative programs
  • Liquidity risk: $172.8 million in cash, equivalents, and marketable securities projected to fund operations at least through 2027

Generated from the filing text; verify against the original. 10-K vs 10-Q vs 8-K

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