10-Q quarterly report · filed Apr 29, 2026

AGIOS PHARMACEUTICALS, INC. (AGIO) Q1 2026 10-Q Quarterly Report

Short answer

AGIOS PHARMACEUTICALS, INC. (AGIO) filed its Q1 2026 10-Q quarterly report on Apr 29, 2026 for the quarter ended Mar 31, 2026. Quarterly revenue was $21M (up 137.7% year over year) with net income of −$99M.

Q1 2026 key financials · XBRL

Revenue
$21M
+137.7% YoY
Net income
−$99M
−11.0% YoY
Operating margin
-530.3%
EPS (diluted)
−$1.69
−9.0% YoY

Source: XBRL data from the AGIOS PHARMACEUTICALS, INC. (AGIO) Q1 2026 10-Q on SEC EDGAR. USD.

AGIOS PHARMACEUTICALS, INC. Q1 2026 10-Q analysis

AI summary of MD&A and risk factor updates

Risk Factors

  • AQVESME™ U.S. launch in late January 2026 created commercialization risk, including prescribing barriers from its FDA-required REMS
  • Product safety risk heightened by AQVESME™ boxed warning for potential hepatocellular injury
  • Mitapivat development risk centers on pending approvals for thalassemia in the EU and SCD in the United States
  • Revenue concentration risk, with PYRUKYND® and AQVESME™ generating $20.7 million in first-quarter 2026 net product revenue
  • Licensing obligation risk includes up to $130.0 million in potential Alnylam development and regulatory milestones plus tiered royalties

Generated from the filing text; verify against the original. 10-K vs 10-Q vs 8-K

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