10-Q quarterly report · filed Nov 6, 2025

Zymeworks Inc. (ZYME) Q3 2025 10-Q Quarterly Report

Short answer

Zymeworks Inc. (ZYME) filed its Q3 2025 10-Q quarterly report on Nov 6, 2025 for the quarter ended Sep 30, 2025. Quarterly revenue was $28M (up 72.6% year over year) with net income of −$20M.

Q3 2025 key financials · XBRL

Revenue
$28M
+72.6% YoY · −43.3% QoQ
Net income
−$20M
+34.3% YoY · −946.0% QoQ
Operating margin
-80.1%
EPS (diluted)
−$0.26
+33.3% YoY · −966.7% QoQ

Source: XBRL data from the Zymeworks Inc. (ZYME) Q3 2025 10-Q on SEC EDGAR. USD.

Zymeworks Inc. Q3 2025 10-Q analysis

AI summary of MD&A and risk factor updates

Risk Factors

  • New risk: European Commission granted conditional marketing authorization of Ziihera® in July 2025, contingent on ongoing Phase 3 trial results
  • Material update: FDA accelerated approval of Ziihera® in Nov 2024 requires confirmatory trial; failure may lead to market removal impacting royalties
  • Regulatory risk: NMPA conditional approval in May 2025 for zanidatamab depends on ongoing confirmatory clinical benefit verification
  • Operational risk: Discontinuation of ZW171 clinical program in Sep 2025 after dose escalation phase due to unfavorable benefit-risk profile
  • Financial risk: Dependence on milestone payments and royalties from Jazz’s zanidatamab commercialization; no other product revenue as of Sept 30, 2025

Generated from the filing text; verify against the original. 10-K vs 10-Q vs 8-K

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