Tarsus Pharmaceuticals, Inc. (TARS) FY2025 10-K Annual Report

Filed: Feb 23, 2026
Health Care
Biological Products, (No Diagnostic Substances)SEC EDGAR

Tarsus Pharmaceuticals, Inc. (TARS) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 23, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Tarsus Pharmaceuticals, Inc. FY2025 10-K Analysis

Business Overview

  • Core business model: Development and commercialization of therapeutics addressing root causes of eye diseases, beginning with FDA-approved XDEMVY for Demodex blepharitis launched August 2023
  • New product emphasis: Advancement of TP-04 for ocular rosacea with Phase 2 trial initiated December 2025; TP-05 oral tablet for Lyme disease prophylaxis with Phase 2 planned for Q2 2026
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Management Discussion & Analysis

  • Revenue $451.4M full year 2025 from XDEMVY sales, up from zero in 2024, delivering 400,000 bottles in 2025
  • Net loss $66.4M in 2025 versus $115.6M in 2024 and $135.9M in 2023, operating expenses to increase with commercial expansion
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Risk Factors

  • Risk from OBBB Act tax reform, enacted July 2025, with $2.1M state income tax due to nonconforming states' capitalization requirements
  • China geopolitical risk from reliance on China Out-License with $86.1M proceeds and up to $100M sales milestones and royalties exposure
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Tarsus Pharmaceuticals, Inc. FY2025 Key Financial Metrics
XBRL

Revenue

$451M

+146.7% YoY

Net Income

-$66M

+42.5% YoY

Operating Margin

-15.7%

+5018bp YoY

Net Margin

-14.7%

+4845bp YoY

ROE

-19.3%

+3212bp YoY

Total Assets

$562M

+49.1% YoY

EPS (Diluted)

$-1.59

+48.2% YoY

Operating Cash Flow

-$12M

+85.0% YoY

Source: XBRL data from Tarsus Pharmaceuticals, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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