SOLENO THERAPEUTICS INC (SLNO) FY2025 10-K Annual Report

Filed: Feb 25, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

SOLENO THERAPEUTICS INC (SLNO) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 25, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

SOLENO THERAPEUTICS INC FY2025 10-K Analysis

Business Overview

  • Core business model: Biopharmaceutical company developing and commercializing novel therapeutics for rare diseases, with initial focus on Prader-Willi syndrome (PWS)
  • New product: FDA approval and first commercial sales of VYKAT XR (diazoxide choline extended-release tablets) for hyperphagia in PWS patients aged 4 and older in March 2025
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Management Discussion & Analysis

  • No revenue or YoY change figures disclosed
  • No profitability or operating margin data provided
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Risk Factors

  • Regulatory risk: FDA approval of VYKAT XR in March 2025 triggered contingent payments of $7.0 million due Q1 2026
  • Macroeconomic exposure: $50 million outstanding loan with Oxford at 1-month SOFR + 5.50% interest, with $100 million more contingent on mutual consent
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SOLENO THERAPEUTICS INC FY2025 Key Financial Metrics
XBRL

Revenue

$190M

Net Income

$21M

+111.9% YoY

Operating Margin

4.9%

Net Margin

11.0%

ROE

4.6%

+7638bp YoY

Total Assets

$564M

+70.4% YoY

EPS (Diluted)

$0.39

+108.9% YoY

Operating Cash Flow

$47M

+167.7% YoY

Source: XBRL data from SOLENO THERAPEUTICS INC FY2025 10-K filing on SEC EDGAR. All figures in USD.

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