10-K annual report · filed Feb 4, 2026

Regeneron Pharmaceuticals (REGN) FY2025 10-K Annual Report

Short answer

Regeneron Pharmaceuticals (REGN) filed its fiscal 2025 10-K annual report with the SEC on Feb 4, 2026. It reported revenue of $14.3B (+1.0% year over year) and net income of $4.5B.

  • Top risk flagged: Lease financing $720M matures March 2027, full payment due unless extended with lender consent

FY2025 key financial metrics · XBRL

Revenue
$14.3B
+1.0% YoY
Net income
$4.5B
+2.1% YoY
Operating margin
24.9%
−3.2 pp YoY
EPS (diluted)
$41.48
+8.2% YoY
ROE
14.4%
−0.6 pp YoY
Operating cash flow
$5.0B
+12.6% YoY

Source: XBRL data from the Regeneron Pharmaceuticals (REGN) FY2025 10-K on SEC EDGAR. USD.

Regeneron Pharmaceuticals FY2025 10-K analysis

AI summary of each section, grounded in the filing text

Business Overview

  • Core business model: Development, manufacturing, and commercialization of innovative biologic drugs and drug-delivery devices with regulatory approval focus
  • New emphasis on expanding internal manufacturing capacity and establishing fill/finish capabilities amid production constraints and pandemic-related impacts
  • Strategic reliance increased on collaborators and contract manufacturers for bulk production and complex device supply chain management
  • Manufacturing capacity limited to facilities in Rensselaer, NY and Limerick, Ireland; investing in expansion and new fill/finish facility undergoing process validation
  • Noteworthy risk: Loss of U.S. market exclusivity for EYLEA as biosimilars launched May 2024, impacting patent protection and revenue outlook

Management Discussion & Analysis

  • Investment portfolio equity securities decreased to $515.8M (Dec 31, 2025) from $1.307B (Dec 31, 2024)
  • Foreign exchange risk growing due to international sales and operations; foreign currency hedging strategies considered

Risk Factors

  • Lease financing $720M matures March 2027, full payment due unless extended with lender consent
  • Exposure to SOFR-based variable interest rate plus margin tied to debt rating and leverage ratio
  • Liabilities for unrecognized tax benefits $1.578B as of December 31, 2025, with high uncertainty in settlement timing
  • Ongoing R&D and commercialization costs depend on trial outcomes, regulatory approvals, and market potential
  • Contingent payments from collaboration agreements include milestone and royalty payments with unpredictable timing

Generated from the filing text; verify against the original. How to read a 10-K

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