PFE Pfizer Inc

FY2025 10-K
Filed: Feb 26, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

Pfizer Inc (PFE) filed its fiscal year 2025 10-K annual report with the SEC on Feb 26, 2026. This page provides AI-powered analysis of the filing, including business overview, management discussion, risk factors, and key financial metrics from XBRL data.

AI Filing Analysis
FY2025 10-K

Business Overview

  • Global pharma innovator generating 65% of revenues from 12 products >$1B each; Eliquis alone = 13% of total revenues in 2025
  • Chantix returned to U.S. market in 2025 after 2021 recall; Oxbryta voluntarily withdrawn globally following negative benefit-risk assessment
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Management Discussion & Analysis

  • Revenue $62.2B in 2025, up ~$0.7B (~1%) YoY from $63.6B in 2024; international ops $25.5B (41% of total)
  • IRA Medicare Part D Redesign negatively impacted 2025 revenues by ~$1B; Eliquis alone = 13% of total revenues
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Risk Factors

  • IRA Medicare Drug Price Negotiation Program: Eliquis, Ibrance, Xtandi, and Xeljanz selected for Maximum Fair Price; IRA Part D Redesign already hit 2025 revenues ~$1B
  • OBBBA (enacted July 4, 2025) cuts Medicaid/ACA funding; CBO estimates 10M more uninsured, threatening product demand and pricing
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Financial Summary
XBRL

Revenue

$62.6B

Net Income

$7.8B

Net Margin

12.4%

ROE

9.0%

Total Assets

$208.2B

EPS (Diluted)

$1.36

Operating Cash Flow

$11.7B

Source: XBRL data from Pfizer Inc FY2025 10-K filing on SEC EDGAR. All figures in USD.

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