Nuvation Bio Inc. (NUVB) FY2025 10-K Annual Report

Filed: Mar 2, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

Nuvation Bio Inc. (NUVB) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Mar 2, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Nuvation Bio Inc. FY2025 10-K Analysis

Business Overview

  • Core business: Global oncology focused on developing novel small molecule therapies for difficult-to-treat cancers, leveraging medicinal chemistry and clinical data
  • New emphasis: U.S. commercial launch of IBTROZI (taletrectinib) for ROS1+ NSCLC approved June 2025, plus new Eisai partnership for European and other territories in 2026
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Management Discussion & Analysis

  • Revenue and profitability data not disclosed in MD&A section
  • No segment performance details provided
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Risk Factors

  • Regulatory risk: FDA approval and post-approval obligations for IBTROZI (taletrectinib) granted June 11, 2025 for ROS1+ NSCLC treatment
  • Geopolitical risk: Commercial partnerships in Japan (NK) and China (Innovent) expose revenue to MHLW and NMPA regulatory environments
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Nuvation Bio Inc. FY2025 Key Financial Metrics
XBRL

Revenue

$63M

+699.0% YoY

Net Income

-$205M

+64.0% YoY

Operating Margin

-338.7%

+718861bp YoY

Net Margin

-325.3%

+688845bp YoY

ROE

-66.9%

+5552bp YoY

Total Assets

$595M

+10.0% YoY

EPS (Diluted)

$-0.60

+71.6% YoY

Operating Cash Flow

-$173M

-33.0% YoY

Source: XBRL data from Nuvation Bio Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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