Intellia Therapeutics, Inc. (NTLA) FY2025 10-K Annual Report

Filed: Feb 26, 2026
Health Care
In Vitro & In Vivo Diagnostic SubstancesSEC EDGAR

Intellia Therapeutics, Inc. (NTLA) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 26, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Intellia Therapeutics, Inc. FY2025 10-K Analysis

Business Overview

  • Core business: biotechnology firm developing CRISPR-based in vivo genome editing therapies targeting severe diseases
  • New emphasis on Phase 3 products lonvo-z and nex-z for hereditary angioedema and transthyretin amyloidosis, with commercial launch preparation for lonvo-z in H1 2027
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Management Discussion & Analysis

  • No revenue or profitability data provided for fiscal year 2026
  • No segment performance or cash flow details disclosed
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Risk Factors

  • Regulatory risk: potential impact of SEC scrutiny on forward-looking statements disclosed in 2026 10-K
  • Geopolitical/macroeconomic risk: $117.7M common stock shares remain under the amended 2022 Sale Agreement with Jefferies exposure to market volatility
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Intellia Therapeutics, Inc. FY2025 Key Financial Metrics
XBRL

Revenue

$68M

+16.9% YoY

Net Income

-$413M

+20.5% YoY

Operating Margin

-651.7%

+27143bp YoY

Net Margin

-609.9%

+28691bp YoY

ROE

-61.5%

-194bp YoY

Total Assets

$842M

-29.3% YoY

EPS (Diluted)

$-3.81

+27.4% YoY

Operating Cash Flow

-$395M

-13.1% YoY

Source: XBRL data from Intellia Therapeutics, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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