NRIX Nurix Therapeutics, Inc.

FY2025 10-K
Filed: Jan 28, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

Nurix Therapeutics, Inc. (NRIX) filed its fiscal year 2025 10-K annual report with the SEC on Jan 28, 2026. This page provides AI-powered analysis of the filing, including business overview, management discussion, risk factors, and key financial metrics from XBRL data.

AI Filing Analysis
FY2025 10-K

Business Overview

  • Clinical stage biopharma focused on targeted protein degradation using AI-integrated DEL-AI platform for oncology, inflammation, and immunology treatments
  • Advanced lead BTK degrader bexobrutideg in Phase 2 pivotal trial with FDA Fast Track and EMA PRIME designations for relapsed/refractory CLL and WM
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Management Discussion & Analysis

  • No revenue figures or profitability metrics disclosed in provided text
  • No segment performance data available
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Risk Factors

  • Regulatory risk: FDA partial clinical hold on zelebrudomide enrollment in 2023 due to manufacturing change, lifted in August 2024
  • Macroeconomic risk: Uncertainty from inflation, interest rates, tariffs, debt ceiling risks, and global conflict impacts clinical trials, supply chain, personnel
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Financial Summary
XBRL

Revenue

$84M

Net Income

-$264M

Operating Margin

-340.2%

Net Margin

-314.9%

ROE

-49.1%

Total Assets

$688M

EPS (Diluted)

$-3.05

Operating Cash Flow

-$249M

Source: XBRL data from Nurix Therapeutics, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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