Moderna (MRNA) FY2025 10-K Annual Report

Filed: Feb 20, 2026
Health Care
Biological Products, (No Diagnostic Substances)SEC EDGAR

Moderna (MRNA) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 20, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Moderna FY2025 10-K Analysis

Business Overview

  • Core business: Development and commercialization of mRNA-based vaccines and therapeutics across infectious diseases, oncology, and rare diseases
  • New product: Launch of mNEXSPIKE COVID vaccine in Q3 2025, now leading US retail product; ongoing filings for flu+COVID and flu-only vaccines in multiple regions
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Management Discussion & Analysis

  • Revenue $1.944B, down 40% YoY ($3.236B in 2024); net product sales $1.818B, down 42% YoY ($3.109B in 2024) due to lower COVID vaccine demand
  • Operating loss $3.074B vs $3.945B; cost of sales $868M (48% of net product sales) vs $1.464B (47%); R&D $3.132B down 31%, SG&A $1.018B down 13%
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Risk Factors

  • Regulatory risk: FDA refusal-to-file letter on seasonal flu vaccine mRNA-1010; amended BLA accepted with PDUFA date August 5, 2026
  • Geopolitical risk: COVID and RSV vaccine manufacturing now onshored in US, Australia, UK, and Canada under government agreements for local supply and pandemic preparedness
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Moderna FY2025 Key Financial Metrics
XBRL

Revenue

$1.9B

-39.9% YoY

Net Income

-$2.8B

+20.8% YoY

Operating Margin

-158.1%

-3622bp YoY

Net Margin

-145.2%

-3512bp YoY

ROE

-32.6%

+4bp YoY

Total Assets

$12.3B

-12.8% YoY

EPS (Diluted)

$-7.26

+21.8% YoY

Operating Cash Flow

-$1.9B

+37.6% YoY

Source: XBRL data from Moderna FY2025 10-K filing on SEC EDGAR. All figures in USD.

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