10-K annual report · filed Mar 5, 2026

Liquidia Corp (LQDA) FY2025 10-K Annual Report

Short answer

Liquidia Corp (LQDA) filed its fiscal 2025 10-K annual report with the SEC on Mar 5, 2026. It reported revenue of $158M (+1031.2% year over year) and net income of −$69M.

  • Top risk flagged: Cybersecurity risk with potential material disruption of product development programs and financial losses due to IT system failures or data breaches

FY2025 key financial metrics · XBRL

Revenue
$158M
+1031.2% YoY
Net income
−$69M
+47.1% YoY
Operating margin
-32.5%
+834.2 pp YoY
EPS (diluted)
−$0.80
+51.8% YoY
ROE
-154.0%
+14.7 pp YoY
Operating cash flow
−$36M
+61.8% YoY

Source: XBRL data from the Liquidia Corp (LQDA) FY2025 10-K on SEC EDGAR. USD.

Liquidia Corp FY2025 10-K analysis

AI summary of each section, grounded in the filing text

Business Overview

  • Core business model: Development and commercialization of inhaled treprostinil therapies for PAH and PH-ILD leveraging proprietary PRINT particle engineering technology
  • New product launch: FDA approved and commercialized YUTREPIA inhalation powder in May-June 2025, designed for higher dosing and improved lung delivery
  • Strategic emphasis: Positioning YUTREPIA as first-choice prostacyclin across PAH and PH-ILD, targeting dose titration beyond existing inhaled therapies like Tyvaso
  • Quantitative metric: YUTREPIA studied at doses up to 424 mcg QID, significantly higher than 64 mcg max dose for Tyvaso DPI, enabling extended inhaled therapy use
  • Noteworthy filing fact: YUTREPIA developed via 505(b)(2) pathway faces ongoing patent litigation by United Therapeutics seeking FDA approval withdrawal

Management Discussion & Analysis

  • Revenue $158.3M in 2025 vs $14.0M in 2024; product sales $148.3M from YUTREPIA launches, service revenue down 28% to $10.0M
  • Operating loss improved to $(51.4)M in 2025 vs $(121.3)M in 2024; SG&A rose 93% to $157.2M, R&D decreased 18% to $39.3M
  • Best segment: Product sales $148.3M in 2025; worst segment: Service revenue declined 28% to $10.0M
  • Cash $190.7M end 2025; net cash from financing $59.7M; CapEx $4.3M; license payment $2.0M; no buybacks or dividends disclosed
  • Outlook risks: FDA approval maintenance, YUTREPIA commercialization success, pump availability constraint on Treprostinil Injection, high R&D costs for L606 development

Risk Factors

  • Cybersecurity risk with potential material disruption of product development programs and financial losses due to IT system failures or data breaches
  • Board Audit Committee oversight of cybersecurity risks with regular management reporting on security controls and incident response effectiveness
  • Dependence on head of IT with 25+ years cybersecurity experience managing day-to-day information security and threat detection operations
  • Incident response led by CEO, CFO, General Counsel, and supported by external legal and cybersecurity advisors to contain and mitigate breaches
  • Potential reputational risk and unauthorized release of confidential information impacting business and financial condition

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