Kymera Therapeutics, Inc. (KYMR) FY2025 10-K Annual Report

Filed: Feb 26, 2026
Health Care
Biological Products, (No Diagnostic Substances)SEC EDGAR

Kymera Therapeutics, Inc. (KYMR) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 26, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Kymera Therapeutics, Inc. FY2025 10-K Analysis

Business Overview

  • Core business: Clinical-stage biopharma specializing in targeted protein degradation (TPD) oral small molecules for immunology and serious diseases
  • New products: Initiated Phase 2b trials for KT-621 (oral STAT6 degrader) in atopic dermatitis and asthma; Phase 1 trial started for KT-579 (oral IRF5 degrader)
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Management Discussion & Analysis

  • No revenue or profitability figures disclosed in MD&A section
  • No segment performance or cash flow details provided
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Risk Factors

  • Regulatory risk: FDA approval timing and success uncertainty for STAT6, IRF5, and IRAK4 programs affecting clinical development and commercialization
  • Macroeconomic risk: Potential capital exhaustion before 2029 despite $1.62B cash, risking delays in R&D and clinical trials
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Kymera Therapeutics, Inc. FY2025 Key Financial Metrics
XBRL

Revenue

$39M

-16.7% YoY

Net Income

-$311M

-39.1% YoY

Operating Margin

-891.1%

-33526bp YoY

Net Margin

-794.0%

-31847bp YoY

ROE

-19.7%

+708bp YoY

Total Assets

$1.7B

+78.2% YoY

EPS (Diluted)

$-3.69

-23.8% YoY

Operating Cash Flow

-$233M

-19.7% YoY

Source: XBRL data from Kymera Therapeutics, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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