iRhythm Holdings, Inc. (IRTC) FY2025 10-K Annual Report

Filed: Feb 19, 2026
Health Care
Surgical & Medical Instruments & ApparatusSEC EDGAR

iRhythm Holdings, Inc. (IRTC) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 19, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

iRhythm Holdings, Inc. FY2025 10-K Analysis

Business Overview

  • Core business model: Design, development, and commercialization of long-term continuous ambulatory cardiac monitoring (ACM) services using patch-based ECG biosensors with proprietary AI analytics
  • New product emphasis: Introduction of smaller, lighter Zio monitor System with Bluetooth and breathable adhesive, enhancing patient compliance and data quality vs prior Zio XT
  • Strategic shift: Expanding ACM adoption beyond cardiology into primary care and integrated delivery networks to capture earlier-stage patient populations with undiagnosed arrhythmias
  • Quantitative highlights: ~2,400 employees as of Dec 31, 2025; ~40% penetration of core U.S. ambulatory cardiac monitoring market; over 12 million patient reports generated
  • Noteworthy fact: Clinical studies (CAMELOT and AVALON) covering >700,000 diagnostic-naive patients demonstrate Zio LTCM Service’s highest diagnostic yield and lower costly hospitalizations than competitors

Management Discussion & Analysis

  • Revenue $747.1M, up 26% YoY from $591.8M driven by volume increases and new Zio AT customer growth
  • Operating margin -8% in 2025 vs -20% in 2024, loss from operations improved by $58.1M to ($57.4M)
  • Best performing segment: iRhythm Services volume growth with significant Zio AT revenue increase; no specific segment dollar detailed for worst performance
  • Cash flow from operations $80.9M vs $3.4M YoY; invested $277.1M in investing activities including $347.9M marketable securities purchases; financed with $12.6M cash from financing activities, down from $511.4M in 2024
  • Management notes macroeconomic uncertainty, higher contractual allowance reserves due to payer claim denials, expects liquidity sufficiency for 12 months, terminated Verily collaboration to focus on clinical-grade wearables

Risk Factors

  • No specific regulatory or legal risk disclosed in the risk factors section
  • No geopolitical or macroeconomic threat with concrete exposure detailed
  • Operational risk: dependency on Nasdaq Global Select Market listing under symbol "IRTC" for liquidity and capital access
  • Competitive risk: no named competitor or technology disruption identified in provided text
  • Financial risk: no dividends declared, retaining all funds to finance growth, no issuer repurchases

iRhythm Holdings, Inc. FY2025 Key Financial Metrics
XBRL

Revenue

$747M

+26.2% YoY

Net Income

-$45M

+60.7% YoY

Gross Margin

70.6%

+171bp YoY

Operating Margin

-7.7%

+1183bp YoY

Net Margin

-6.0%

+1318bp YoY

ROE

-29.2%

+9545bp YoY

Total Assets

$1.0B

+9.5% YoY

EPS (Diluted)

$-1.39

+61.7% YoY

Operating Cash Flow

$81M

+2285.3% YoY

Source: XBRL data from iRhythm Holdings, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

Get deeper insights on iRhythm Holdings, Inc.

Access full AI analysis, insider trading data, fund holdings, and cross-signal detection on SignalX.