IDEAYA Biosciences, Inc. (IDYA) FY2025 10-K Annual Report

Filed: Feb 17, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

IDEAYA Biosciences, Inc. (IDYA) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 17, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

IDEAYA Biosciences, Inc. FY2025 10-K Analysis

Business Overview

  • Core oncology precision medicine with focus on synthetic lethality and antibody-drug conjugates (ADCs) targeting molecularly defined solid tumors
  • New Phase 3 neoadjuvant trial for darovasertib in primary uveal melanoma initiated, targeting eye preservation and vision improvement
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Management Discussion & Analysis

  • Collaboration revenue $218.7M in 2025 vs $7.0M in 2024, up 3,024% driven by Servier License Agreement
  • Net loss $113.7M in 2025 vs $274.5M in 2024; loss decreased 59%, operating expenses up 13% to $378.0M
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Risk Factors

  • Regulatory risk: Servier License Agreement contract assets increased $6.0M, indicating dependency on this agreement's terms and regulatory compliance timing
  • Macroeconomic threat: Operating cash used $71.1M in 2025 and $247.6M in 2024, showing high cash burn amid volatile financing environment
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IDEAYA Biosciences, Inc. FY2025 Key Financial Metrics
XBRL

Revenue

$219M

+3024.4% YoY

Net Income

-$114M

+58.6% YoY

Operating Margin

-72.8%

+459823bp YoY

Net Margin

-52.0%

+386911bp YoY

ROE

-11.1%

+1480bp YoY

Total Assets

$1.1B

-1.3% YoY

EPS (Diluted)

$-1.28

+61.9% YoY

Operating Cash Flow

-$71M

+71.3% YoY

Source: XBRL data from IDEAYA Biosciences, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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