ERAS Erasca, Inc.

FY2025 10-K
Filed: Mar 12, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

Erasca, Inc. (ERAS) filed its fiscal year 2025 10-K annual report with the SEC on Mar 12, 2026. This page provides AI-powered analysis of the filing, including business overview, management discussion, risk factors, and key financial metrics from XBRL data.

AI Filing Analysis
FY2025 10-K

Business Overview

  • Core business: Precision oncology company focused exclusively on discovering and developing therapies targeting RAS/MAPK pathway-driven cancers
  • New emphasis: Clinical-stage programs ERAS-0015 (pan-RAS molecular glue) and ERAS-4001 (pan-KRAS inhibitor) initiated INDs May 2025, first clinical data expected H1/H2 2026
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Management Discussion & Analysis

  • No revenue generated; net loss $124.5M in 2025 vs $161.7M in 2024, improving by $37.1M
  • Operating expenses down to $140.9M in 2025 from $179.6M in 2024; R&D expense 22% lower at $92.9M vs $115.4M
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Risk Factors

  • Regulatory risk from compliance with EU Clinical Trials Regulation (CTR) effective January 31, 2025 impacting multi-center trial approvals
  • Geopolitical risk from potential delays and cost increases due to evolving U.S. tariff and import/export regulations affecting operations
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Financial Summary
XBRL

Net Income

-$125M

ROE

-38.3%

Total Assets

$396M

EPS (Diluted)

$-0.44

Operating Cash Flow

-$95M

Source: XBRL data from Erasca, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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