DYN Dyne Therapeutics, Inc.

FY2025 10-K
Filed: Mar 2, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

Dyne Therapeutics, Inc. (DYN) filed its fiscal year 2025 10-K annual report with the SEC on Mar 2, 2026. This page provides AI-powered analysis of the filing, including business overview, management discussion, risk factors, and key financial metrics from XBRL data.

AI Filing Analysis
FY2025 10-K

Business Overview

  • Core business model: Development of product candidates for rare muscle diseases, leveraging manufacturing agreements with CMOs
  • New master manufacturing services agreements in 2025 securing $169.9M total fees committed through 2027 for product candidate components
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Management Discussion & Analysis

  • No revenue disclosed, focus on clinical development expenses for z-rostudirsen, z-basivarsen, FSHD and Pompe programs
  • No profitability or margin figures provided, expenses expected to increase with ongoing activities
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Risk Factors

  • FDA clinical hold on z-rostudirsen IND in Jan 2022, delaying trial start until July 2022 clearance
  • Geopolitical and market risk from clinical and regulatory approval uncertainty in US and EU (FDA, EMA) regulatory agencies
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Financial Summary
XBRL

Net Income

-$446M

ROE

-45.9%

Total Assets

$1.2B

EPS (Diluted)

$-3.47

Operating Cash Flow

-$403M

Source: XBRL data from Dyne Therapeutics, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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