Dyne Therapeutics, Inc. (DYN) FY2025 10-K Annual Report
Dyne Therapeutics, Inc. (DYN) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Mar 2, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.
Dyne Therapeutics, Inc. FY2025 10-K Analysis
Business Overview
- • Core business model: Development of product candidates for rare muscle diseases, leveraging manufacturing agreements with CMOs
- • New master manufacturing services agreements in 2025 securing $169.9M total fees committed through 2027 for product candidate components
Management Discussion & Analysis
- • No revenue disclosed, focus on clinical development expenses for z-rostudirsen, z-basivarsen, FSHD and Pompe programs
- • No profitability or margin figures provided, expenses expected to increase with ongoing activities
Risk Factors
- • FDA clinical hold on z-rostudirsen IND in Jan 2022, delaying trial start until July 2022 clearance
- • Geopolitical and market risk from clinical and regulatory approval uncertainty in US and EU (FDA, EMA) regulatory agencies
Dyne Therapeutics, Inc. FY2025 Key Financial MetricsXBRL
Net Income
-$446M
▼ -40.6% YoY
ROE
-45.9%
▲ +450bp YoY
Total Assets
$1.2B
▲ +71.7% YoY
EPS (Diluted)
$-3.47
▼ -3.0% YoY
Operating Cash Flow
-$403M
▼ -37.9% YoY
Source: XBRL data from Dyne Therapeutics, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.
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