Dianthus Therapeutics, Inc. /DE/ (DNTH) FY2025 10-K Annual Report

Filed: Mar 9, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

Dianthus Therapeutics, Inc. /DE/ (DNTH) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Mar 9, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Dianthus Therapeutics, Inc. /DE/ FY2025 10-K Analysis

Business Overview

  • Core business: Development of claseprubart and DNTH212 biopharmaceutical candidates reliant on outsourced manufacturing and clinical trial services
  • New emphasis: Impact of the BIOSECURE Act (Dec 2025) restricting collaborations with certain Chinese biotech firms, including sole manufacturer WuXi Biologics
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Management Discussion & Analysis

  • No revenue reported, no year-over-year change disclosed
  • Net loss reported; specific profitability or margin figures not provided
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Risk Factors

  • Regulatory risk: Dependence on FDA approval for claseprubart and DNTH212 with uncertain timing and outcomes for clinical trial phases and marketing approvals
  • Geopolitical risk: License and development agreements with Tenacia Biotechnology for Greater China involving clinical trial cost sharing and milestone payments up to $15 million
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Dianthus Therapeutics, Inc. /DE/ FY2025 Key Financial Metrics
XBRL

Revenue

$2M

-67.3% YoY

Net Income

-$162M

-91.1% YoY

Operating Margin

-8739.3%

-710560bp YoY

Net Margin

-7973.3%

-661056bp YoY

ROE

-32.9%

-880bp YoY

Total Assets

$531M

+42.0% YoY

EPS (Diluted)

$-4.20

-64.7% YoY

Operating Cash Flow

-$129M

-65.1% YoY

Source: XBRL data from Dianthus Therapeutics, Inc. /DE/ FY2025 10-K filing on SEC EDGAR. All figures in USD.

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