10-K annual report · filed Feb 11, 2026

Bristol Myers Squibb (BMY) FY2025 10-K Annual Report

Short answer

Bristol Myers Squibb (BMY) filed its fiscal 2025 10-K annual report with the SEC on Feb 11, 2026. It reported revenue of $48.2B (−0.2% year over year) and net income of $7.1B.

  • Top risk flagged: FDA approval of Breyanzi in Dec 2025 for relapsed/refractory MZL after ≥2 systemic therapies, impacting market access and revenue

FY2025 key financial metrics · XBRL

Revenue
$48.2B
−0.2% YoY
Net income
$7.1B
+178.8% YoY
EPS (diluted)
$3.46
+178.5% YoY
ROE
38.2%
+93.0 pp YoY
Operating cash flow
$14.2B
−6.8% YoY

Source: XBRL data from the Bristol Myers Squibb (BMY) FY2025 10-K on SEC EDGAR. USD.

Bristol Myers Squibb FY2025 10-K analysis

AI summary of each section, grounded in the filing text

Business Overview

  • Core business model focused on oral immunomodulatory and oncology drugs, primarily treating multiple myeloma and CML
  • FDA-approved volume-unlimited generics launched for Revlimid (2026), pomalidomide generics entering U.S. (Mar 2026), dasatinib generics active since Sept 2024
  • Strategic shift marked by drastic revenue declines (up to 78% U.S. for Abraxane) due to generic erosion and Medicare Part D redesign
  • Total expenses reduced 31% to $38.9B in 2025 driven by 72% drop in acquired IPRD spend and 14% SG&A cuts post productivity initiatives
  • No excess inventory in U.S. distribution channels despite widespread generic competition, reflecting tightly managed supply and demand forecasting

Management Discussion & Analysis

  • Forward-looking: Management highlights multiple regulatory approvals, pipeline expansion via acquisitions and collaborations including Orbital Therapeutics and BioNTech, new radiopharmaceutical facility opened

Risk Factors

  • FDA approval of Breyanzi in Dec 2025 for relapsed/refractory MZL after ≥2 systemic therapies, impacting market access and revenue
  • Exposure to Japan's approval landscape with multiple key drug approvals by Ministry of Health Labour and Welfare in 2025, critical for Asia Pacific growth
  • Dependence on strategic collaboration with BioNTech for co-development of pumitamig, a PD-L1/VEGF-A bispecific in oncology
  • Competitive threat from BioNTech partnership leveraging innovative bispecific technology against IO market leaders Opdivo and Yervoy
  • $2.0B expected cost savings by 2027 through expanded 2025 strategic productivity initiatives impacting R&D, manufacturing, and commercial functions

Generated from the filing text; verify against the original. How to read a 10-K

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