Axogen, Inc. (AXGN) FY2025 10-K Annual Report

Filed: Feb 24, 2026
Health Care
Electromedical & Electrotherapeutic ApparatusSEC EDGAR

Axogen, Inc. (AXGN) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 24, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Axogen, Inc. FY2025 10-K Analysis

Business Overview

  • Core business: Development and commercialization of innovative peripheral nerve regeneration and repair technologies
  • New product: FDA-approved Avance® acellular nerve scaffold (December 3, 2025), launching Q2 2026, replacing Avance® Nerve Graft
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Management Discussion & Analysis

  • Revenue $225.2M, up 20.2% YoY from $187.3M driven by unit volume, price, and product mix changes
  • Gross margin 74.3% vs 75.8% YoY, gross profit $167.4M up 17.9% from $142.0M, impacted by $1.9M one-time FDA BLA costs
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Risk Factors

  • Regulatory risk: FDA accelerated approval of Avance Products contingent on confirmatory trials with milestones through 2031; failure may cause withdrawal or restrictions
  • Operational risk: Avance manufacturing relies on variable donated cadaveric tissue, causing potential lot failures, product recalls, and supply shortages
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Axogen, Inc. FY2025 Key Financial Metrics
XBRL

Revenue

$225M

+20.2% YoY

Net Income

-$16M

-57.6% YoY

Gross Margin

74.3%

-148bp YoY

Operating Margin

-3.5%

-173bp YoY

Net Margin

-7.0%

-165bp YoY

ROE

-12.2%

-260bp YoY

Total Assets

$222M

+8.8% YoY

EPS (Diluted)

$-0.34

-47.8% YoY

Operating Cash Flow

$812,000

-82.1% YoY

Source: XBRL data from Axogen, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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